Term
| Rifampicin (side effects) |
|
Definition
-hepatitis
-rash
-GI upset
-intermittent Rx can give rise to flu like symptoms
-drug interactions
-OCP/prednisolone |
|
|
Term
|
Definition
-rash
-peripheral neuropathy
-hepatitis |
|
|
Term
|
Definition
| - Dose related optic neuropathy |
|
|
Term
| Pyrazinamide (side effects) |
|
Definition
-hepatitis
-facial flushing
-rash
-nausea & anorexia
-arthralgia
-high uric acid |
|
|
Term
| Expectations of treatment of TB |
|
Definition
2 weeks: non infectious (number of viable organisms)
2 weeks: Temperature settled
1 month: Weight gain
2 months: Sputum culture negative |
|
|
Term
| Reasons for false positive test |
|
Definition
|
|
Term
| Reasons for false negative test |
|
Definition
20% of patients with known TB…may later become positive
In HIV (60%)
Protein malnutrition
Sarcoid
Intercurrent viral infections
Corticosteroids
Delayed result in indochinese |
|
|
Term
| Interferon gamma test (advatages) |
|
Definition
Very sensitive
Specific antigen |
|
|
Term
| Interferon gamma test (disadvatages) |
|
Definition
Requires living cells
Time consuming
False positives from other mycobacteria
Detects exposure, rather than infection |
|
|
