Term
| What is migration time of dividing cells as they move to the top of the stratum corneum? |
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Definition
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Term
| What is contained in Dermis? |
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Definition
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Term
| What are dermis and epidermis are bound by projections that grow up and down respectively? |
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Definition
| Dermal Papillae and rete ridges |
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Term
| What is simple wound definiton? |
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Definition
No major tissue loss
No associated frature
No injury to deeper structures
No gross contaminaiton or debris
Wound edges are easily opposed |
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Term
| What is the example of simple wound? |
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Definition
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Term
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Definition
soft tissue loss
major neurovascular injury
Fracture
Gross contamination
Impregnated debris
Wound edges not easily opposed and my require healing by secondary intention |
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Term
| What is the example of complex wound? |
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Definition
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Term
| What is the incised wound? |
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Definition
| Linear wound with regular margins...typical sx wound |
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Term
| What is laceration wound? |
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Definition
| Traumatic tearing of tissue, irregular margins & beveling of the edges |
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Term
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Definition
| Loss of epidermal surface without loss of dermal integrity |
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Term
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Definition
| Soft tissue injury with no break in epidermal integrity with echymosis |
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Term
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Definition
| Penetrating injury with little surface disruption. |
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Term
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Definition
| break in the continuity of bone or cartilage |
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Term
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Definition
| Loos of flap of tissue deeper than the dermis |
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Term
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Definition
| Rapid and severe squeezing which causes diffuse cellular damage with or without break in epidermis |
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Term
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Definition
| Traumatic loss of tissue from digit or extremity |
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Term
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Definition
Incisional wound
Little or no crushing, tearing, or avulsing components |
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Term
| What is contaminated wounds? |
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Definition
Wounds with a higher degree of soft tissue damage which are more predisposed to infection
Or a clean wound left exposed for >6hrs |
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Term
| How do you manage contanminated wounds? |
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Definition
Wound can be converted from contaminated to clean by appropriate debridement and copious lavage
Contaminated wounds should Not be primarily closed until they are converted to a clean wound |
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Term
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Definition
Exhibit clinical signs of infection or gross contamination
These wounds can not be closed until they are transformed to a clean wound by abx, debridement, and local wound care |
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Term
| What is wounds with soft tissue loss? |
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Definition
Degloving injuries, slicing injuries, compression injuries with a brusting type laceration
These wounds may require skin grafting after converting them to a clean wound |
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Term
| When is inflammation or substrate (lag phase)? |
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Definition
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Term
| WHen is proliferation or fribroblastic phases (repair)? |
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Definition
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Term
| What is remodeling or maturation phase? |
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Definition
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Term
| What are cardinal signs of inflammaiton? |
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Definition
Tumor/swelling
Dolor/pain
Rubor/redness
Calor/Heat
Loss of Function |
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Term
| What cells presented in Inflammarory or Substrate phase? |
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Definition
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Term
| What cells presented in Inflammarory or Substrate phase? |
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Definition
| Mast cells release histamine for vasodilation and cellular migration |
|
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Term
| what is mediators of inflammation? |
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Definition
| histamine: vascular permeability, major source from the mast cell and platelet |
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Term
| What is mediators of inflammation? |
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Definition
| Serotonin, plasma kinins, prostaglandins |
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Term
| What happened in cell activation? |
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Definition
| Reduced inflammatory responses profoundly affect subsequent healing |
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Term
| What happened in cell activation? |
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Definition
| Steroid use: affects cell migration, proliferation, and angiogenesis. Can be partially reversed by Vit. A administration |
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Term
| What cells is predominant in proliferation phase? |
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Definition
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Term
|
Definition
| collagen causes an increase in wound tensile strength to reduce size by bringing wound edges closer together |
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Term
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Definition
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Term
| At the 15 days proliferation phase |
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Definition
| wound reaches 35% of it;s original strength-14th day. Tensile strength of wound equals strength of suture and therefore can be removed |
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Term
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Definition
| Abnormal collagen proliferation, stays within margins of original scar: neutralize and soften after 18 months |
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Term
|
Definition
| fibrous tissue hyperplasia: extends beyond margins of original scar: nerve entrapment, painful |
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Term
| What is primary wound healing? |
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Definition
| Healing by first intention, sutured wound/steri strips: occur within hrs after repairing a surgical incision |
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Term
| What is secondary wound healing? |
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Definition
| wound edges are separated, results in an inflammatory response that is more intense than with primary wound healing with a larger quantity of granulatomatous tissue is fabricated because of the need for wound closure |
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Term
| What is delayed primary healing? |
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Definition
| 2 intention with delayed 1st closure, in the case of contaminated wounds |
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Term
| What are the factors affecting wound healing? |
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Definition
Adequate blood supply and tissue perfusion (oxygen tension),
Healing deficiency is evident in the maturation phase |
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Term
| Condition that affect tissue perfusion? |
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Definition
PVD:
Smoking: nicotine is vasoconstrictor, and hemoglobin carries carbon monoxide instead of oxygen |
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