Term
| Antineoplastic & chemotherapeutic drugs. |
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Definition
| This class of drugs stop cancerous activity of malignant cels. Act s. characteristics unique to malignant cells. |
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Term
Cell-cycle-nonspecific. (CCNS)
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Definition
| Antineoplastic agents that act during any phase of the cell cycle. They kill during the dividing or resting phase. |
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Term
| Cell cycle specific. (CCS) |
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Definition
| Antineoplastic agents that act during specific phase of the cell cycle. Effective vs. rapidly growing cancer cells. |
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Term
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Definition
| The percentage of the cancer cells that are actively dividing. |
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Term
| Cells are divding rapidly. |
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Definition
| When there is a high growth fraction cells are: |
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Term
| Cells are dividing slowly. |
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Definition
| When there is a low growth fraction cells are: |
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Term
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Definition
| In general antineoplastic agens are ore effective against cancer cells with a? |
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Term
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Definition
| Time required for the # f cancer cells to divide. |
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Term
Antineoplastic drugs
(Cell cycle-nonspecific) |
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Definition
| Cyclophosphamide (Cytoxan), Cisplatin, Carboplatin, & Doxorubicin (Adriamycin) are examples of what drug class? |
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Term
Antineoplastic
(Cell cycle specific) |
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Definition
| 5-Fluorouracil, Vincristine, & Vinblastine are examples of what class of drugs? |
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Term
Body surface area.
(BSA is dtermined from BW in kg using charts) |
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Definition
| What are calculaions of antineoplastic drugs based on? |
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Term
| 72 hrs and disposed of properly. |
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Definition
| When handling antineoplastic waste, is is considered contaminated for how long? |
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Term
| Vertical airflow hood with PPE. |
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Definition
| Reconstitution of antineoplastic agents is done in a? |
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Term
same area should not be used again with in a 2 hour period.
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Definition
When administering antineoplastic agents, an IV catheter placement muct be a good stick &?
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Term
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Definition
Is it a good idea for pregnant women to handle antineoplastic agents?
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Term
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Definition
| Should immuno-compromised people handle antineoplastics? |
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Term
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Definition
| You should not do this while handling antineoplastic drugs? |
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Term
| Biologic response modifiers (BRM's) |
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Definition
| agents used in conjuntion with antineoplastic agents to enhance the body's immune system. |
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Term
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Definition
| Group of naturally-occuring proteins that have antitumor & antiviral effects. |
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Term
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Definition
| Immune enhancer group of chemicals that play various roles in the immune system. |
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Term
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Definition
| A chemical used in treatment of fibrosarcoma & MCT's (mass cell tumors) in dogs and cats They stimulate macrophage activity. |
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Term
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Definition
| Identical immunoglobulin molecules that have cytotoxic effects on tumor cells. |
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Term
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Definition
| Drugs that work mainly by interfering with one of te stages of the cell cycle or by affecting cell messangers. Used primarily to treat immune-mediated disorders in which the immune system is overactive. |
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Term
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Definition
| Atopica, Imuran, & Cytoxan are examples of what types of drugs? |
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Term
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Definition
| L-asparaginase (Elspar) works by making asparagine unavailable to malignant cells and is an example of an? |
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Term
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Definition
| These control the growth of tumor cells. Example: Toceranib (Palladia) |
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Term
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Definition
| Adverse reaction to these types of drugs include: bone marrow supression, GI effects, Alopecia, Infertiity, Cardiotoxicity. |
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