Term
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Definition
| normal, physiological response at site of trauma; tightly adhered against wall; layered, part of vessel wall healing |
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Term
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Definition
| From blood coagulation at site of vascular pathology; associated w blood vessel wall; adherent to lumen, layered due to effects of blood flow |
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Term
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Definition
| traveling mass in blood; doesn't have to be pathologic (thromboembolus) |
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Term
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Definition
| blood loss into tissues; pathologic |
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Term
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Definition
| blood loss outside body or into cavity; nonadherent, homogeneous; current jelly |
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Term
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Definition
| alternating RBC-rich and RBC-poor zones in a thrombus |
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Term
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Definition
| Predisposing Factors to thrombus: abnormalities in 1) blood flow (stagnation, obesity) 2) blood composition (hypercoagulable, leukemia, oral contraceptives, hyperlipidemia) 3) vessel wall (inflammatory vasculitis). Thrombosis requires 2 of these |
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Term
| Affects of EC on thrombosis |
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Definition
| Anti-thrombotic: inhibition of platelet aggregation, inhibition of coagulation, fibrinolysis |
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Term
| Steps in Arterial hemostasis |
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Definition
| 1) spasm (vasoconstriction, epinephrine in lidocaine, cocaine) 2) Primary plug (activated platelets) 3) Secondary plug (platelets + fibrin) |
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Term
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Definition
| Endothelial cells release TF when they are injured-->clot formation |
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Term
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Definition
| Endothelial cells release TF when they are injured-->clot formation |
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Term
| Venous thrombus characteristics |
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Definition
| RBC and fibrin, loosely adherent, soft, red |
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Term
| Arterial thrombus characteristics |
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Definition
| Platelet rich, tightly adherent, pale, firm. in arterial circulation, high flow rates lead to more shear induced aggravation of platelets |
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Term
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Definition
| Resolution, emobolization, organization, recanalization, occlusion |
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Term
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Definition
| Deep venous thrombosis, amniotic fluid, fat from bone fracture, foreign material, tumor emboli, air embolism from port, R-->L shunt can lead to systemic embolism |
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Term
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Definition
| No blood flow to a wedge shaped region of the lung from a PE that occludes central artery |
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Term
| #1 cause of systemic infarct |
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Definition
| L Atrial fibrillation because the LA appendage doesnt empty well and can form thrombi |
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Term
| Specific Tissue involvement of a thromboembolism depends on |
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Definition
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Term
| Tissue consequences of thrombi and emboli |
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Definition
| Ischemia (insufficient tissue perfusion), hypoxia (insufficient tissue oxygen), infarction (death due to hypoxia), infart healing (Parenchymal regeneration; heart cannot regenerate-fibrosis and scarring occurs instead.) |
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Term
| Renal infarct characteristics |
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Definition
| Pale, wedge-shaped, organization (healing and inflammation), occurs at edges due to collaterals |
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Term
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Definition
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Term
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Definition
| thrombosis, embolism, aneurysm burst-->hemorrhage, ischemia. Does not heal-->fibrosis. Wedge shaped |
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Term
| Most commonly occluded coronary artery |
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Definition
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Term
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Definition
| grayish-purple oozing of blood from collaterals after a thromboembolism to the SMA |
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Term
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Definition
| Fusiform (aligned with axis-full form), Saccular (outpouching of a sack) |
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Term
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Definition
| actually a hematoma contained by extravascular connective tissue |
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Term
| Aortic Dissections are associated with |
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Definition
| Marfan, Ethler-Danlos, HTN, aortic valve disease, atherosclerosis (wall weakness) |
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Term
| Aortic Dissection: caused by, leads to |
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Definition
| vessel wall weakness, increased blood forces-->intimal entry site with dissection along medial layer (outer 2/3) |
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Term
| Aortic Dissection: complications |
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Definition
| hemorrhage, branch occlusion |
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Term
| Aortic aneurysm: associations |
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Definition
| Wall weakness: Marfan, Ethler-Danlos and increased blood forces |
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Term
| Aortic aneurysm: common site |
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Definition
| AAA, below renal arteries |
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Term
| Aortic aneurysm: complications |
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Definition
| accumulate thrombosis because of stagnant blood, rupture-->80% fatality |
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Term
| Aortic aneurysm: treatment |
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Definition
| Endovascular repair, interposition graft |
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Term
| Aortic dissection: classification |
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Definition
| Type A: any aortic involvement proximal to subclavian-->more urgent because it can occlude coronary arteries and carotid (brain, heart); type B |
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Term
| Screening recommendations for aortic aneurysm |
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Definition
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