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trueger
drug tox
65
Other
Not Applicable
06/06/2006
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Term
Atropine-like side
 Definition
Tricyclic
Term
Cardiac toxicity
 Definition
Doxorubicin (Adriamycin), daunorubicin
Term
Coronary vasospasm
 Definition
Cocaine
Term
Cutaneous flushing
 Definition
Niacin, Ca2+ channel blockers, adenosine, vancomycin
Term
Torsades de pointes
 Definition
Class III (sotalol), class IA (quinidine) antiarrhythmics, cisapride
Term
Agranulocytosis
 Definition
Clozapine, carbamazepine, colchicine
Term
Aplastic anemia
 Definition
Chloramphenicol, benzene, NSAIDs
Term
Gray baby syndrome
 Definition
Chloramphenicol
Term
Hemolysis in G6PD-deficient patients
 Definition
Sulfonamides, isoniazid (INH), aspirin, ibuprofen, primaquine, nitrofurantoin
Term
Thrombotic complns
 Definition
OCPs (e.g., estrogens and progestins)
Term
Cough
 Definition
ACE inhibitors (losartan––no cough)
Term
Pulmonary fibrosis
 Definition
Bleomycin, amiodarone, busulfan
Term
Acute cholestatic hepatitis
 Definition
Macrolides
Term
Focal to massive hep necr
 Definition
Halothane, valproic acid, acetaminophen, Amanita phalloides
Term
Hepatitis
 Definition
INH
Term
Pseudomembranous colitis
 Definition
Clindamycin, ampicillin
Term
Adrenocortical insuff
 Definition
Glucocorticoid withdrawal (HPA suppression)
Term
Gynecomastia
 Definition
Spironolactone, Digitalis, Cimetidine, chronic Alcohol use, estrogens, Ketoconazole
Term
Hot flashes
 Definition
Tamoxifen
Term
Gingival hyperplasia
 Definition
Phenytoin
Term
Osteoporosis
 Definition
Corticosteroids, heparin
Term
Photosensitivity
 Definition
Sulfonamides, Amiodarone, Tetracycline (SAT for a photo)
Term
SLE-like syndrome
 Definition
Hydralazine, INH, Procainamide, Phenytoin (it’s not HIPP to have lupus)
Term
Tendonitis, tendon rupt, cart dmg in kids
 Definition
Fluoroquinolones
Term
Fanconi’s syndrome
 Definition
Expired tetracycline
Term
renall Interstitial nephritis
 Definition
Methicillin
Term
Hemorrhagic cystitis
 Definition
Cyclophosphamide, ifosfamide
Term
Cinchonism
 Definition
Quinidine, quinine
Term
Diabetes insipidus
 Definition
Lithium, demeclocycline
Term
Seizures
 Definition
Bupropion, imipenem/cilastatin
Term
Tardive dyskinesia
 Definition
Antipsychotics
Term
Tricyclic
 Definition
Atropine-like side
Term
Doxorubicin (Adriamycin), daunorubicin
 Definition
Cardiac toxicity
Term
Cocaine
 Definition
Coronary vasospasm
Term
Niacin, Ca2+ channel blockers, adenosine, vancomycin
 Definition
Cutaneous flushing
Term
Class III (sotalol), class IA (quinidine) antiarrhythmics, cisapride
 Definition
Torsades de pointes
Term
Clozapine, carbamazepine, colchicine
 Definition
Agranulocytosis
Term
Chloramphenicol, benzene, NSAIDs
 Definition
Aplastic anemia
Term
Chloramphenicol
 Definition
Gray baby syndrome
Term
Sulfonamides, isoniazid (INH), aspirin, ibuprofen, primaquine, nitrofurantoin
 Definition
Hemolysis in G6PD-deficient patients
Term
OCPs (e.g., estrogens and progestins)
 Definition
Thrombotic complns
Term
ACE inhibitors (losartan––no cough)
 Definition
Cough
Term
Bleomycin, amiodarone, busulfan
 Definition
Pulmonary fibrosis
Term
Macrolides
 Definition
Acute cholestatic hepatitis
Term
Halothane, valproic acid, acetaminophen, Amanita phalloides
 Definition
Focal to massive hep necr
Term
INH
 Definition
Hepatitis
Term
Clindamycin, ampicillin
 Definition
Pseudomembranous colitis
Term
Glucocorticoid withdrawal (HPA suppression)
 Definition
Adrenocortical insuff
Term
Spironolactone, Digitalis, Cimetidine, chronic Alcohol use, estrogens, Ketoconazole
 Definition
Gynecomastia
Term
Tamoxifen
 Definition
Hot flashes
Term
Phenytoin
 Definition
Gingival hyperplasia
Term
Corticosteroids, heparin
 Definition
Osteoporosis
Term
Sulfonamides, Amiodarone, Tetracycline (SAT for a photo)
 Definition
Photosensitivity
Term
Hydralazine, INH, Procainamide, Phenytoin (it’s not HIPP to have lupus)
 Definition
SLE-like syndrome
Term
Fluoroquinolones
 Definition
Tendonitis, tendon rupt, cart dmg in kids
Term
Expired tetracycline
 Definition
Fanconi’s syndrome
Term
Methicillin
 Definition
renall Interstitial nephritis
Term
Cyclophosphamide, ifosfamide
 Definition
Hemorrhagic cystitis
Term
Quinidine, quinine
 Definition
Cinchonism
Term
Lithium, demeclocycline
 Definition
Diabetes insipidus
Term
Bupropion, imipenem/cilastatin
 Definition
Seizures
Term
Antipsychotics
 Definition
Tardive dyskinesia
Term
disulfiram like rxn
 Definition
Metronidazole, certain cephalosporins, procarbazine, sulfonylureas
Term
nephrtox/neuro tox
 Definition
Polymyxins
Term
Nephrotoxicity/ototox
 Definition
Aminoglycosides, loop diuretics, cisplatin
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