Term
|
Definition
diffuse br ain, mult lesions, often bil
bx=fibrocystic
no incr risk CA |
|
|
Term
diffuse br ain, mult lesions, often bil
bx=fibrocystic
no incr risk CA |
|
Definition
|
|
Term
| histo types of fibrocystic dz |
|
Definition
fibrosis: hyperplasia of br stroma
cystic: fluid filled
sclerosing: up acini & intralob fibr
epith hyperplasia:up number of epith layers in term duct, up risk CA w. atyp cells. >30yo |
|
|
Term
|
Definition
most common br tumor <25yo
sm, mobile, firm w. sharp edges
up sz & tenderness w. preg
not premalign |
|
|
Term
|
Definition
lg, bulky mass of CT & cysts
may have leaflike projns |
|
|
Term
|
Definition
tumor of lactiferous ducts
nipple d/c |
|
|
Term
most common br tumor <25yo
sm, mobile, firm w. sharp edges
up sz & tenderness w. preg
not premalign |
|
Definition
|
|
Term
lg, bulky mass of CT & cysts
may have leaflike projns |
|
Definition
|
|
Term
tumor of lactiferous ducts
nipple d/c |
|
Definition
|
|
Term
|
Definition
common post MP
arise fr mammary duct epith or lobular glands
overexpr estr/prog Rs or erb-B2 (Her-2) an EGF R |
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
| ductal, cheesy cons due to centr necr |
|
|
Term
|
Definition
| lymph involvement, poor progn (br CA) |
|
|
Term
|
Definition
|
|
Term
|
Definition
| fleshy, cellular, lympho infil, good progn |
|
|
Term
|
Definition
ecz patches on nipple
paget cells: lg, clr halo, suggest underlying CA
also seen in vulva |
|
|
Term
|
Definition
| gender, age, menarche bf 12. primigrav post 30, mp post 50, famhx |
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
| ductal, cheesy cons due to centr necr |
|
Definition
|
|
Term
| lymph involvement, poor progn (br CA) |
|
Definition
|
|
Term
|
Definition
|
|
Term
| fleshy, cellular, lympho infil, good progn |
|
Definition
|
|
Term
ecz patches on nipple
paget cells: lg, clr halo, suggest underlying CA
also seen in vulva |
|
Definition
|
|
Term
| gender, age, menarche bf 12. primigrav post 30, mp post 50, famhx |
|
Definition
|
|
Term
|
Definition
5a reductase inh
bph, prom hair growth |
|
|
Term
|
Definition
non-ster comp inh of testR
prostate CA |
|
|
Term
| ketoconazole, spironolactone |
|
Definition
inh steroid synth
used in polycystic ov to prev hirsutism |
|
|
Term
| sildenafil, vardenafil MOA |
|
Definition
inh cGMP phosphodiesterase -> up cGMP
sm m relax in corpus cav -> up BF -> erection |
|
|
Term
| sildenafil, vardenafil clin use |
|
Definition
|
|
Term
| sildenafil, vardenafil SE |
|
Definition
| HA, flushing, dyspepsia, blue-green vision, life-threat hypoTN w. nitrates |
|
|
Term
|
Definition
GnRH analog
ag if puls, antag if cont |
|
|
Term
|
Definition
infert (puls)
pros CA (cont, w. flutamide), uterine fibroids |
|
|
Term
|
Definition
|
|
Term
|
Definition
partial ag at estrRs in pit
prevents nl feedback inh
-> up rel LH & FSH -> stim ovulation |
|
|
Term
|
Definition
|
|
Term
|
Definition
| hot flashes, ov enlgment, mult simult pregs, vis disturbs |
|
|
Term
|
Definition
|
|
Term
|
Definition
| abortifactant (prev impln) |
|
|
Term
|
Definition
| heavy bleeding, GI (N,V,anorex), abd pain |
|
|
Term
|
Definition
reliable
dn risk endometr & ov CA
dn inc ectopic prg
dn pelvic infns
reg menses |
|
|
Term
5a reductase inh
bph, prom hair growth |
|
Definition
|
|
Term
non-ster comp inh of testR
prostate CA |
|
Definition
|
|
Term
inh steroid synth
used in polycystic ov to prev hirsutism |
|
Definition
| ketoconazole, spironolactone |
|
|
Term
inh cGMP phosphodiesterase -> up cGMP
sm m relax in corpus cav -> up BF -> erection |
|
Definition
| sildenafil, vardenafil MOA |
|
|
Term
|
Definition
| sildenafil, vardenafil clin use |
|
|
Term
| HA, flushing, dyspepsia, blue-green vision, life-threat hypoTN w. nitrates |
|
Definition
| sildenafil, vardenafil SE |
|
|
Term
GnRH analog
ag if puls, antag if cont |
|
Definition
|
|
Term
infert (puls)
pros CA (cont, w. flutamide), uterine fibroids |
|
Definition
|
|
Term
|
Definition
|
|
Term
partial ag at estrRs in pit
prevents nl feedback inh
-> up rel LH & FSH -> stim ovulation |
|
Definition
|
|
Term
|
Definition
|
|
Term
| hot flashes, ov enlgment, mult simult pregs, vis disturbs |
|
Definition
|
|
Term
|
Definition
|
|
Term
| abortifactant (prev impln) |
|
Definition
|
|
Term
| heavy bleeding, GI (N,V,anorex), abd pain |
|
Definition
|
|
Term
|
Definition
daily
no STD protn
up TGs
depr, wt gn, N, HTN
hypercoag |
|
|
