Term
| Estrogens, oral contraceptives, raloxifine |
|
Definition
| increased TBG binding capacity (decreases circulating hormone stores) |
|
|
Term
| Androgens, salicylates, glucocorticoids |
|
Definition
| decreased TBG binding capacity (increases circulating hormone stores) |
|
|
Term
| Propylthiouracil, propranolol, glucocorticoids, amiodarone |
|
Definition
| decreased peripheral conversion T4 to T3 (decreased circulating hormone) |
|
|
Term
| Phenytoin, phenobarbital, arbamazepine, rifampin, sertraline |
|
Definition
| Enzyme induction (decreased circulating hormone) |
|
|
Term
| cholestyramine, colestipol, ferrous sulfate, suralfate, calcium aluminum-containing antacids |
|
Definition
| decreased bioavailability due to bound Levothyroxdine (decreased circulating hormone) |
|
|
Term
|
Definition
| increased catabolism Vitamin K- dependent clotting factors (when hormone is low it decreases the breakdown of clotting factors and requires an increase in Warfarin |
|
|
Term
| histamine bockers and proton pump inhibitors |
|
Definition
| decreased acid secretion (increased pH = decreased absorption of thyroid medication) |
|
|
