Term
| How does cimetidine (TAGAMET) work? |
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Definition
| Competitively block H2 receptors on parietal cells, reducing gastric acid secretion. |
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Term
| How does cimetidine interact with CYP enzymes |
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Definition
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Term
| Cimetidine may decrease absorption of which drugs? |
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Definition
| AZOLEs: itraconazole, ketoconazole; AVIRs: indinavir, atazanavir; Tyrosine kinase inhibitors: dasatinib, gefitinib, erlotinib |
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Term
| What are the practice points for cimetidine? |
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Definition
| Consider using a different H2 antagonist. |
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Term
| What are the side effects of long term corticosteroid use? |
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Definition
| weight gain, infection, GI ulcers/bleeding, osteoporosis, weight gain, weight gain, insomnia, oedema/hypertension, steroidal withdrawal syndrome: fatigue, muscle stiffness/pain, joint pain, fever. |
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Term
| what are the symptoms of steroid withdrawal syndrome? |
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Definition
| fatigue, muscle stiffness/pain, joint pain, fever. |
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