Term
| Which receptor detects pain? |
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Definition
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Term
| Which receptor detects touch |
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Definition
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Term
When you have pain what happens with your:
1. pupils
2. glucose
3. GI |
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Definition
1. pupil dilates (SNS!!)
2. hyperglycemia (SNS!!)
3. decrease gut motility and increase hydrogen ion secretion (SNS) |
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Term
| Pain causes a decrease in blood flow to what areas of the body? |
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Definition
| Well pain modulates the SNS. So SNS activation results in decrease blood flow to kidney's, viscera and skin. |
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Term
| What are the nerve fibers that carry the pain signals |
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Definition
| A delta fibers and C fibers |
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Term
| T / F: Pain fibers desensitizes the originating stimulus |
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Definition
| False! We want to keep being informed that our hand is on a hot fire because our body wants to survive! |
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Term
| What chemical causes the most pain |
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Definition
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Term
| Name all the chemicals that illicit a pain stimulus? |
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Definition
1. bradykinin
2. Serotonin
3. histamine
4. K
5. AcH (If released into tissue)
6. protaglandins
7. Substance P
8. Acids |
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Term
| endorphins do what to potassium levels |
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Definition
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Term
| what are the four steps in the pain process |
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Definition
1. transduction
2. transmission
3. perception
4. modulation |
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Term
| which step in the pain process involves the PNS and CNS |
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Definition
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Term
| perception during the pain process occurs where? |
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Definition
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Term
| significant enhancement or suppression of pain perception is done during what process of the pain process |
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Definition
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Term
| What is a vanilloid 1 receptor? |
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Definition
| it is an excitatory Ca and sodium ion receptor found on the peripheral nerve terminal which starts the action potential and transduction of the pain signal. |
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Term
| What receptors inhibit pain transduction? |
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Definition
| cannabinoid and opioid receptors inhibit pain transduction via activation of K channels. |
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Term
| all ________ are free nerve endings but not all ______ are pain receptors |
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Definition
| All pain receptors are free nerve endings but not all free nerve endings are pain recpetors. |
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Term
| A pain receptor is a ______ class of receptors |
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Definition
| free nerve endings (nociceptor) all same thing |
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Term
| List in order from thickest to smallest the sizes of sensory fibers |
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Definition
| A alpha > A beta > A delta > C fiber |
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Term
| which one of the pain fibers is localized? |
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Definition
| A delta fibers are specific to the type of pain and are well localized. We know heat from sharp pinch and where. |
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Term
| The major NT of A delta fibers is? And that NT binds to? |
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Definition
| glutamate; binds to AMPA and NMDA receptors |
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Term
| The major neurotransmitter for C fibers is? Binds to? |
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Definition
| C fiber major NT is substance P; binds to neurokinin-1 receptors. |
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