Term
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Definition
| Carbonyl group is reduced to a hydroxyl group by a reducing agent |
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Term
| How does an Alpha amino acid exist in solution? |
|
Definition
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Term
|
Definition
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Term
|
Definition
Aspartic Acid
Glutamic Acid |
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Term
| What is distinctive about a peptide bond? |
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Definition
Carbon double bond to oxygen
conntcted to Nitrogen bonded to hydrogen |
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Term
| When can Chymotrypsin cleave a protein chain? |
|
Definition
After PHEnylanaline
After TRYptophan
After TYRosine |
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Term
| Where does Trypsin cleave protein chains? |
|
Definition
After ARGinine
After LYSine
EXCEPT wehre followed by PROlein |
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Term
| List 4 means of stabiliztion for a TERTIARY protein. |
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Definition
Covalent bonds: S-S disulfide bonds
Hydrogen bonding
Salt bridge NH3+ C-O-
Hydorphobic between non-polar side chains |
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Term
| Describe a Fibrous protein. |
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Definition
Linear
Insoluble in water
Folds so hydrophobic side chains are on the exterior
Example is Keratin |
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Term
| Describe a Globular Protein. |
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Definition
Spherical
soluble in water-colloid
Hydrophilic side chains ar directed to exterior
Example: Albumin |
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Term
| Describe secondary structure protein |
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Definition
Hydrogen bonding between amide linkages of main chain
alpha helix-spiral clockwise coil held by H bonding between carbonyl of amide and N-H of other
Side chain point outward
Beta pleated sheets
Random coil |
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Term
| Can a secondary protein structure have Beta pleated sheets, alpha helix, and random coils? |
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Definition
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Term
| Name 2 teritary structure proteins |
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Definition
Keratin-fibrous
Albumin-Globular |
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Term
| Describe Quaternary Structure |
|
Definition
2 or more polypeptide chains
Chains are SUBUNITS-identical or different
Conjugated proteins-material other than amino chaines |
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Term
| What structure are Glycoproteins? |
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Definition
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Term
| What structure are lipoproteins and hemoglobin? |
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Definition
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Term
| What is a conjugated protein? |
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Definition
| Protein with a small organic molecule-Quatenary |
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Term
| What is the small organic molecule of a conjugated protein called? |
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Definition
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Term
| Vasopressin and Oxytocin are examples of which structure of proteins? |
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Definition
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Term
| How many combinations are possible in a chain of "n" amino acids? |
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Definition
| 20 raised to the power of "n" |
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Term
| Name amino acids with a phenyl ring. |
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Definition
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Term
| Which amino acid contains a thiol? |
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Definition
| Cystein can form disulfide bonds |
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Term
| List some ways to denature a protein |
|
Definition
Heat
6M aqueous Urea
Detergent
Reducing agent-mercaptoethanol
Heavy metal ions Pb, Hg, Cd
alcohols 70% ethanol |
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