Term
|
Definition
| antibiotic that is effective against a very large variety of organisms |
|
|
Term
| nosocomial infections are usually _____ to at least one type of antibiotic |
|
Definition
|
|
Term
| Which organism is resistant to most meds? |
|
Definition
|
|
Term
| What drug can treat MRSA? |
|
Definition
|
|
Term
| Which bacteria is resistant to vancomycin? |
|
Definition
|
|
Term
| What 3 factors decrease the chance of resistance? |
|
Definition
better pt & dr education
accurate diagnosis
targeted treatment |
|
|
Term
| Selection of anti-infectives is based on: |
|
Definition
1. hepatic/renal function
2. Age of pt
3. Prego/Lactation
4. Likelihood of developing resistance
5. known med allergies |
|
|
Term
| allergic hypersensitivity symptoms: |
|
Definition
|
|
Term
| allergic hypersensitivity symptoms: |
|
Definition
|
|
Term
| 3 adverse reactions to anti-infectives: |
|
Definition
Allergic hypersensitivity
Direct toxicity
Indirect toxicity/superinfection |
|
|
Term
| direct toxicity symptoms: |
|
Definition
ototoxicity
nephrotoxicity
hepatotoxicity
blood dyscrasias
phlebitis
phototoxicity |
|
|
Term
| indirect toxicity/superinfection def |
|
Definition
| a new infection with different resistant bacteria or fungi as a result of killing the normal flora in the intestines or mucous membranes, esp with broad-spectrum antibiotics |
|
|
Term
| where do you find the most up to date info on vaccines? |
|
Definition
| Center for Disease Control and Prevention |
|
|
Term
|
Definition
| gram negative & positive bacteria |
|
|
Term
| what bacteria is generally resistant to aminoglycosides? |
|
Definition
|
|
Term
| examples of aminoglycosides |
|
Definition
amikacin
gentamicin
tobramicin |
|
|
Term
| aminoglycosides are usually administered: |
|
Definition
| IV or IM = not thru GI tract |
|
|
Term
| how do you determine appropriate dosing for aminoglycosides? |
|
Definition
|
|
Term
| aminoglycoside serious side effects |
|
Definition
nephro & oto toxicity
resp paralysis
headache, tremor, lethargy, numbness, seizures |
|
|
Term
| aminoglycoside contraindications: |
|
Definition
prego/lact
< renal function
dehydration
infants & elderly |
|
|
Term
|
Definition
close med supervision
I&Os
watch kidney or hearing problems |
|
|
Term
|
Definition
| semisynthetic antibiotic derivatives produced by a fungus |
|
|
Term
| are cephalosporins narrow or broad spectrum? |
|
Definition
| broad - gram neg & pos bacteria |
|
|
Term
| 1st generation cephalosporins: |
|
Definition
| effective against gram+ bacteria, causing pneumonias & UTI's |
|
|
Term
| 2nd-generation cephalosporins: |
|
Definition
gram +&- bacteria
example: bacterial influenza |
|
|
Term
| 3rd generation cephalosporin: |
|
Definition
effective against more gram negative bacteria
ex: STDs (gonorrhea) |
|
|
Term
| 4th generation cephalosporins |
|
Definition
Maxipime
gram + & - bacteria |
|
|
