Term
| A class of drugs that decreases REM sleep. Withdrawal from this drug has a rebound effect to give you nightmares. |
|
Definition
|
|
Term
| This class of drugs binds to a site on the GABA A channel and alters it to allow for more effective GABA binding. |
|
Definition
|
|
Term
| An odd side effect of BZs is... |
|
Definition
| Paradoxical excitement and CNS stimulation. |
|
|
Term
| A second generation anxiolytic that is a partial agonist as 5HT 1A receptors is... |
|
Definition
| Buspirone. This drug works over time which is the only downside to this drug. |
|
|
Term
| This drug increases aldehye dehydrogenase. |
|
Definition
| Disulfram. It causes flushing, nasuea, vomiting and hypotension when combined with alcohol. |
|
|
Term
| A competitive benzodiazepine receptor antagonist. |
|
Definition
|
|
Term
| This drug class causes you to spend more time in stage 2 of sleep over stages 3 and 4. Also increased brief awakenings, and an increase in total sleep time. You will also notice decreased REM and sleep latency. |
|
Definition
|
|
Term
| A person who wakes up several times a night and has difficulty getting to sleep may be prescribed... |
|
Definition
| Zolpidem (Ambien). Note that you should only use this drug for 5 weeks. |
|
|
Term
| This drug shortens sleep latency and had a shorter half life so it can be used to help insomnia even as late as midnight. |
|
Definition
| Zaleplon (Sonata). This drug works on a GABA receptor, so you should not mix alcohol with it. |
|
|
Term
| A second generation hypnotic that is effective up to 12 months. |
|
Definition
|
|
Term
| This drug helps Delayed Phase Sleep Disorder. Can be used in the elderly, ICU, and those who travel. |
|
Definition
|
|
Term
| This second generation hypnotic is a melatonin agonist (MT1) |
|
Definition
|
|
Term
| These three benzos under go phase II inactivation. What are the three drugs and why is this significant? |
|
Definition
Outside The Liver
Oxazepam, Temazepan, Lorazepam
These drugs are good to give to the elderly and people with liver disease |
|
|
Term
| Between the benzos and barbs which ones increase the frequency of channel opening and which ones increase the duration of channel opening? |
|
Definition
Benzos increase the frequency
Barbs increase the duration |
|
|
Term
| Name two drugs you would consider giving for Generalized Anxiety Disorder. |
|
Definition
|
|
Term
| Name drugs would you give for stress-related anxiety |
|
Definition
| Any benzos would be the preferred drug. |
|
|
Term
| Drugs or classes of drugs you would give for panic attacks |
|
Definition
| Alprazolam, SSRIs, TCAs, MAO-Is |
|
|
Term
| Drugs you could give for PTSD |
|
Definition
SSRIs and MAO-Is.
Possibly benzos |
|
|
Term
| What do you NOT give for social phobias? |
|
Definition
| NO BENZOs FOR SOCIAL PHOBIA! |
|
|
Term
| So it turns out Elvis is not dead but just had sudden onset Agoraphobia. What drug would you prescribe? |
|
Definition
|
|
