Term
| antiproteinase-3 (anti-PR3) |
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Definition
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|
Term
| antimyeloperoxidase (anti-MPO) |
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Definition
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Term
|
Definition
| plasma exchange, immunosuppressive therapy |
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Term
| Treatment for lupus nephritis class III or IV (acute nephritis with hematuria / proteinuria ) |
|
Definition
| 6 months of monthly IV cyclophosphamide, followed by cyclophosphamide q 3 months x 2 years |
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Term
| Membranoproliferative glomerulonephritis is associated with which autoimmune diseases |
|
Definition
| Sjogrens, SLE (and HCV, infective endocarditis and certain malignancies) |
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Term
| IgA nephropathy treatment |
|
Definition
| ACE / ARB if protein : Cr < 1, if > 1, pulse steroids +/- alkylating agent |
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Term
|
Definition
| nephrotic syndrome; large, echogenic kidneys; renal insufficiency; rapid progression to ESKD |
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Term
| Treatment for fibrillary and immunotactoid glomerulonephritis |
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Definition
| Plasmapheresis, prednisone, cytotoxic agents, NSAIDs, and colchecine |
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|
Term
| Nephrotic syndrome findings |
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Definition
| urine protein : Cr > 3.5, hypoalbuminuria, hyperlipidemia, lipiduria, edema, hypercoagulability |
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|
Term
| Nephritic syndrome findings |
|
Definition
| hematuria, oliguria, HTN, renal insufficiency, proteinuria |
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Term
| Tubuluointerstitial disease findings |
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Definition
| Slowly prgressive renal dizsease, bland urine sediment, protein excretion < 2g/day, atrophic, echogenic kidneys on US |
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Term
| Acute tubulointerstitial disease findings |
|
Definition
| pyuria, eosinophilia, eosinphiluria, AKI |
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Term
| Clinical features of autosomal-recessive PKD |
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Definition
| Hepatic fibrosis and portal HTN |
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|
Term
| Treatment for HTN in ARPKD |
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Definition
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|
Term
| Alport syndrome presentation |
|
Definition
| nephrotic range proteinuria, hearing and visual abnormalities |
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|
Term
| Fabry disease presentation |
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Definition
| Mild proteinurea, slow deteriation of renal function, cutaneous angiokeratomas, painful parasthesias of hands, premature CAD |
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Term
|
Definition
| IV recombinant alpha-galactosidase A |
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Term
| Acute interstitial nephritis UA findings |
|
Definition
| leukocyte casts, eosinophils, protein : Cr < 2.5 |
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|
Term
|
Definition
| Increased ureteric dilatation, increased protein excretion to 150-300 mg/day |
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Term
|
Definition
| not recommended unless SLE has been inactive for > 6 months |
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|
Term
| What should be suspected if HTN, elevated Cr and proteinuria on first antepartum visit? |
|
Definition
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|
Term
| Time to wait after renal transplant for pregnancy |
|
Definition
| 1 to 2 years, and only if Cr < 2 |
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|
Term
| UA findings in interstitial nephritis |
|
Definition
| sterile pyuria and WBC casts |
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|
Term
| UA findings in nephrosclerosis |
|
Definition
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|
Term
| Sodium restriction with advanced CKD |
|
Definition
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|
Term
| Expected daily Cr excretion for men |
|
Definition
|
|
Term
| Expected daily Cr excretion for women |
|
Definition
|
|
Term
| GFR is validation for what kind of renal disease |
|
Definition
| CKD. Not validated in AKI for healthy persons. |
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|
Term
| Gold standard for estimation of GFR in healthy persons or with AKI |
|
Definition
| Radionuclide kidney clearance scanning |
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|
Term
|
Definition
| Infection, AIN, chronic tubulointerstitial disease, acute kidney transplant rejection |
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|
Term
| Erythrocyte casts are pathognomonic for... |
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Definition
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|
Term
| Most common indications for renal biopsy |
|
Definition
| Nephrotic syndrome, acute transplant rejection, acute glomerulonephritis |
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|
Term
| Conivaptan and tolvaptan are... |
|
Definition
| vasopressin antagonists, approved for hypervolemic and euvolemic hyponatremia, but NOT hypovolemic hyponatremia. |
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|
Term
| Clinical symptoms of hypokalemia |
|
Definition
| flaccid paralysis, rhabdo, smooth muscle dysfunction, polyuria, polydipsia, renal failure, glucose intolerance |
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|
Term
| Severe, symptomatic hypophosphatemia happens most often in... |
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Definition
|
|
Term
| Hypophosphatemia manifests as... |
|
Definition
| severe weakness, rhabdo, hemolysis, left left shift on O2 curve |
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|
Term
| Low anion gap is caused by |
|
Definition
| Unmeasured anions - unmeasured cations = AG. Low albumin or increased cationic light chains will cause a low anion gap. |
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|
Term
| Lab findings with extra-renal metabolic acidosis... |
|
Definition
large, negative urine anion gap.
Examples are diarrhea, loss of pancreatic or biliary secretions. Gap is caused by increased urine ammonium secretion. |
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|
Term
| Treatment for proximal RTA |
|
Definition
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|
Term
|
Definition
| Correction of hypoalemia and alkalai tx. |
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|
Term
| Treatment for ethylene glycol and methanol poisoning |
|
Definition
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|
Term
| Unexplained anion gap in setting of APAP should make you think of... |
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Definition
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|
Term
| Acute compensation in respiratory alkalosis is __ HCO3 for __ pCO2 |
|
Definition
| 2 decrease in HCO3 for every 10 decrease in arterial PCO2 |
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|
Term
| Chronic compensation in respiratory alkalosis is __ HCO3 for __ pCO2 |
|
Definition
| 5 decrease in HCO3 for every 10 decrease in arterial PCO2 |
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