Term
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Definition
| Alpha 1, Alpha 2, Beta 1, Beta 2 |
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Term
| Alpha 1 adrenergic receptors |
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Definition
| Target: Alpha Male: eyes, vessels, male sex organs, prostate, and bladder all muscular contraction (ejaculation in the sex organs, dilate pupils) |
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Term
| Alpha 2 adrenergic receptors |
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Definition
| Target: presynaptic nerve terminals (inhibit transmitter release) |
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Term
| Beta 1 adrenergic receptors |
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Definition
| Blood pressure increase: increased heart rate/AV node conduction velocity, increased cardiac contractility, and renin release in the kidneys |
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Term
| Beta 2 adrenergic receptors |
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Definition
| Benefitz the tissues: bronchi dilation, arteriole dilation, glycogenolysis in the muscles and liver, and relaxation of the uterus |
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Term
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Definition
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Term
| nicotinic N cholinergic receptors |
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Definition
| found on all autonomic ganglia and in the adrenal medulla: stimulate postganglionic nerves, and epinephrine release |
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Term
| muscarinic cholinergic receptors |
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Definition
Skin: sweat
Eyes: miosis
Lungs: brochi constriction/mucus production
Heart: decreased heart rate
Vessels: vasodilation
GI: increased motility
GU: voiding, erection |
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Term
| Adrenergic neurotransmitters |
|
Definition
Epinephrine: all alpha and beta, not dopamine
Norepinephrine: a1, a2, b1
Dopamine: a1, b1, & dopamine |
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Term
|
Definition
| a more selective drug binds fewer types of receptors --> fewer side-effects |
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Term
| transmitter life: synthesis |
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Definition
ACh: choline + acetyl CoA
NE: NE precursors
Epi: chromaffin cells convert norepi --> epi w/ specialized enzymes |
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Term
| transmitter life: degradation |
|
Definition
ACh: acetylcholinesterase--> acetate & choline
NE: not degraded
Epi: hepatic metabolism terminates action |
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Term
|
Definition
| M for Muscle: found at NMJ, contracts muscle |
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|
Term
| cholinergic neurotransmitters |
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Definition
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