Term
| 3rd month of embryogenesis cells migrate to |
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Definition
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Term
| Chief source of cell formation B4 transitioning to bone marrow |
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Definition
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Term
| At birth, almost exclusive source of blood cells |
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Definition
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Term
| At 18 yrs., marrow production is in |
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Definition
| Vertebrae, Ribs, Sternum, Pelvis & proximal epiphysis of humerus & femur |
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Term
| Amount of blood in your body |
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Definition
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Term
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Definition
exerts osmotic pressure pulse & maintains vascular volume
maintains colloid osmotic pressure preventing plasma loss from capillaries, |
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Term
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Definition
plasma protein
makes antibodies to fight off pathogens
perform many enzyme functions and are responsible for innate and acquired immunity (immunoglobulin). |
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Term
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Definition
| polymerizes into long fibrin threads during blood coagulation, forming clots |
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Term
| The major activities during erythropoiesis: |
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Definition
Proliferation
Hemoglobin production
Compression of & extrusion of nucleus
Production of enzymes to maintain correct ionic balance for biconcave shape |
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Term
| Erythropoiesis [EPO] is carefully regulated primarily by |
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Definition
| erythropoietin released by the kidneys in response to low oxygen tension |
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Term
| RBC houses some 300 million HB molecules |
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Definition
| with 4 hemes (or iron linkages) |
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Term
| Spleen removes RBC's after |
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Definition
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Term
| Purpose of Biconcave Shape of erythrocytes |
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Definition
Flexibility in navigating capillaries
Gas exchange - high surface to volume ratio |
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Term
| Iron molecules must be in |
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Definition
| the ferrous state [2+] to bind a molecule of oxygen |
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Term
| hemoglobin synthesis linked to |
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Definition
| iron availability & renal release of hormonal erythropoietin |
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Term
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Definition
is one of the bile salts
the larger family of molecules which are important in dietary fat emulsion.
it's insoluble (won’t dissolve) in plasma
must be transported in blood to the liver attached to albumin |
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Term
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Definition
| erythrocytes smaller than normal; correlates with MCV < 80 fL |
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Term
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Definition
| erythrocytes larger than normal; correlates with MCV > 100 fL |
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Definition
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Definition
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Definition
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Definition
| when the red cell mass remains normal but the plasma volume increases |
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Term
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Definition
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Term
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Definition
Blood loss (acute or chronic)
Impaired RBC Production
Accelerated RBC Destruction(sickle cell) |
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