Term
| Keratin pearls on a skin biopsy |
|
Definition
|
|
Term
| Large rash with bull's-eye appearance |
|
Definition
| Erythema chronicum migrans from Ixodes tick bite (Lyme disease: Borrelia) |
|
|
Term
| Lucid interval after traumatic brain injury |
|
Definition
| Epidural hematoma (middle meningeal artery rupture) |
|
|
Term
Male child
Recurrent infections
No mature B cells |
|
Definition
| Bruton's disease (X-linked agammaglobulinemia) |
|
|
Term
| Mucosal bleeding and prolonged bleeding time |
|
Definition
| Glanzmann's thrombasthenia (defect in platelet aggregation due to lack of GpIIb/IIIa) |
|
|
Term
Multiple colon polyps
Osteomas/soft tissue tumors
Impacted/supernumerary teeth |
|
Definition
| Gardner's syndrome (subtype of FAP) |
|
|
Term
Myopathy (infantile hypertrophic cardiomyopathy)
Exercise intolerance |
|
Definition
| Pompe's disease (lysosomal alpha-1,4-glucosidase deficiency) |
|
|
Term
| Necrotizing vasculitis (lungs) and necrotizing glomerulonephritis |
|
Definition
| Wegener's (c-ANCA positive) and Good Pasture's syndromes (anti-basement membrane antibodies) |
|
|
Term
| Neonate with arm paralysis following difficult birth |
|
Definition
| Erb-Duchenne palsy (superior trunk [C5-C6] brachial plexus injury: "waiter's tip") |
|
|
Term
No lactation postpartum
Absent menstruation
Cold intolerance |
|
Definition
| Sheehan's syndrome (pituitary infaction) |
|
|
Term
Nystagmus
Intention tremor
Scanning speech
Bilateral internuclear ophthalmoplegia |
|
Definition
|
|
Term
| Oscillating slow/fast breathing |
|
Definition
| Cheyne-Stokes respirations (central apnea in CHF or increased intracranial pressure) |
|
|
Term
Painful blue fingers/toes
Hemolytic anemia |
|
Definition
| Cold agglutinin disease (autoimmune hemolytic anemia caused by Mycoplasma pneumoniae, infectious mononucleosis) |
|
|
Term
| Painful, pale, cold fingers/toes |
|
Definition
| Raynaud's syndrome (vasospasm in extremities) |
|
|
Term
| Painful, raised red lesions on palms and soles |
|
Definition
| Osler's node (infective endocarditis) |
|
|
Term
| Painless erythematous lesions on palms and soles |
|
Definition
| Janeway lesions (infective endocarditis) |
|
|
Term
|
Definition
| Cancer of pancreatic head obstructing bile duct |
|
|
Term
Palpable purpura on buttocks/legs
Joint pain
Abdominal pain (child) |
|
Definition
| Henoch-Schonlein purpura (IgA vasculitis affecting skin and kidneys) |
|
|
Term
| Pancreatic, pituitary, parathyroid tumors |
|
Definition
| MEN 1 (autosomal dominant) |
|
|
Term
Pink complexion
Dyspnea
Hyperventilation |
|
Definition
| "Pink puffer" (emphysema: centroacinar [smoking], panacinar [alpha1-antitrypsin deficiency]) |
|
|
Term
Polyuria
Acidosis
Growth failure
Electrolyte imbalances |
|
Definition
| Fanconi's syndrome (proximal tubular reabsorption defect) |
|
|
Term
| Positive anterior "drawer sign" |
|
Definition
| Anterior cruciate ligament (ACL) injury |
|
|
Term
|
Definition
| Horner's syndrome (sympathetic chain lesion) |
|
|
Term
| Pupil accommodates but doesn't react |
|
Definition
| Argyll Robertson pupil (neurosyphilis) |
|
|
Term
| Rapidly progressive leg weakness that ascends (following GI/upper respiratory infection) |
|
Definition
| Guillain-Barre syndrome (autoimmune acute inflammatory demyelinating polyneuropathy) |
|
|
Term
|
Definition
Coxsackie A
Secondary syphilis
Rocky Mountain spotted fever |
|
|
Term
Recurrent colds
Unusual eczema
High serum IgE |
|
Definition
| Hyper-IgE syndrome (Job's syndrome: neutrophil chemotaxis abnormality) |
|
|
Term
| Red "currant jelly" sputum in alcoholic or diabetic patients |
|
Definition
|
|
Term
| Rid, itchy, swollen rash of nipple/areola |
|
Definition
| Paget's disease of the breast (represents underlying neoplasm) |
|
|
Term
| Red urine in the morning, fragile RBCs |
|
Definition
| Paroxysmal nocturnal hemoglobinuria |
|
|
Term
Renal cell carcinoma (bilateral)
Hemangioblastomas
Angiomatosis
Pheochromocytoma |
|
Definition
| von Hippel-Lindal disease (dominant tumor suppressor gene mutation) |
|
|
Term
Resting tremor
Rigidity
Akinesia
Postural instability |
|
Definition
| Parkinson's disease (nigrostriatal dopamine depletion) |
|
|
Term
| Retinal hemorrhages with pale centers |
|
Definition
| Roth's spots (bacterial endocarditis) |
|
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