Term
| Solubility Coefficient of Oxygen |
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Definition
| .003mL/100mL * mmHg of plasma |
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Term
| Solubility Coefficient of CO2 |
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Definition
| .067mL/100mL * mmHg of plasma |
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Term
| How much more soluble is CO2 than O2? |
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Definition
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Term
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Definition
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Term
|
Definition
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Term
| Diffusion coefficient equation |
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Definition
| Cd= Solubility coeff./(sq.root(molecular wt.)) |
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Term
|
Definition
(A*Cd*change in P)/T
A=surface area
Cd=diffusion coefficient
P=pressure
T=thickness of membrane |
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Term
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Definition
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Term
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Definition
diffusion through blood-gas barrier
reaction with hemoglobin |
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Term
| distance for gas diffusion |
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Definition
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Term
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Definition
amount of gas uptake depends entirely on the amount of blood flow
Ex. N2O, O2, CO2 |
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Term
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Definition
amount of gas that enters blood is limited by diffusion alone
ex: CO |
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Term
| Causes of O2 diffusion abnormalities |
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Definition
thickened alveolar capillary membrane
low inhaled partial pressure of O2
exercise |
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Term
| Diffusion capacity of the lung equation |
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Definition
V/(P1-P2)
V=vol gas transfered (diffused)
P1&P2= partial pressures for alveolar & capillary blood |
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Term
| Factors that decrease diffusion capacity of the lung |
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Definition
anemia
reduced lung vol.
restrictive lung disease
loss of alveolar capillary membrane surface
poor distribution of ventilation
increased deadspace
thick alveolar-capillary membrane |
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Term
| Factors that increase diffusion capacity of the lung |
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Definition
increased pulm. capillary blood vol.
polycythemia
supine position
exercise |
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