Term
| What is/are the black box warning(s) for the Stimulants? |
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Definition
| Underlying cardiac problems not previously diagnosed may result in sudden death |
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Term
| Psychosis/mania, aggression/violence, panic attacks, severe anxiety, as well as growth deficits and weight loss are AE's of what drug(s)? |
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Definition
| Stimulants: methylphenidate, dexmethylphenidate, amphetamine and lisdexamfetamine |
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Term
| The height deficit caused by _______ may result in a height loss of ______ and a weight loss of ________. |
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Definition
| caused by stimulants; loss of 1 cm/year for up to 1st 3 yrs of tx, and loss of 3kg in 1st year. |
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Term
| Appetite suppression, insomnia, nausea, stomach acha, dizziness and headache are SEs of _______ |
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Definition
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Term
| What drugs are the stimulants? |
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Definition
| Methylphenidate, dexmethylphenidate, lisdexamfetamine, and amphetamine |
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Term
| Which drug(s) increase Dopamine and Norepinephrine release? |
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Definition
| Methylphenidate, dexmethylphenidate, and amphetamine |
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Term
| Which drug(s) has/have 2D6 and 2B6 interaxns? |
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Definition
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Term
| Methylphenidate is available in what dosage forms? |
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Definition
| Short/intermediate/long acting and transdermal |
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Term
| Which of Methylphenidate's dosage forms may cause GI obstruction? |
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Definition
|
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Term
| Which stimulant(s)s is/are available as generic? |
|
Definition
| methylphenidate and amphetamine |
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Term
| Which stimulant is less likely to suppress appetite or cause tics/insomnia? |
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Definition
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Term
| Nine hours of the methylphenidate patch gives ____ symptom coverage. |
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Definition
|
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Term
| generic differences have been reported for which drug? |
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Definition
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Term
| When comparing SE's, Dexmethylphenidate has less ___ but more _____ compared to Methylphenidate |
|
Definition
| Less headaches, greater GI complications |
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Term
| Amphetamine is available in what dosage forms? |
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Definition
| Short/intermediate/Long acting |
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Term
| Which drug features spansules that can be sprinkled on food, as well as predictable PK? |
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Definition
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Term
| Which drug has more abuse potential, can cause/worsen tics, and suppress growth? |
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Definition
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Term
| Which stimulant is a prodrug of another? |
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Definition
| Lisdexamfetamine is a prodrug of amphetamine. |
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Term
| Which drug features a capsule that can be opened and dissolved in water? |
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Definition
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Term
| When compared to amphetamine, lisdexamphetamine has (more/less/the same) abuse potential. |
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Definition
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Term
| What are the nonstimulant ADHD drugs? |
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Definition
| Atomoxetine, Bupropion, TCAs, Clonidine & guanfacine, Lithium & anticonvulsants, antipsychotics |
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Term
| Which drug(s) is a/are SELECTIVE NE reuptake inhibitor? |
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Definition
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Term
| ______ is non-controlled, has no abuse potential, but has lower efficacy than stimulants. |
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Definition
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Term
| Atomoxetine (can/can't/always must) be combined with a stimulant. |
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Definition
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Term
| Which drug(s) should be avoided within 2 weeks of an MAOI? |
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Definition
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Term
| Which drug(s) may increase BP, cause liver toxicity, change mood as well as decrease appetite, nausea, and HA? |
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Definition
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Term
| Which drug(s) is/are a weak DA and NE reuptake inhibitor, with efficacy close to methylphenidate's? |
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Definition
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Term
| Which drug(s) is/are less toxic than the TCAs, stimulates appetite less, has no risk of abuse and has good response? |
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Definition
|
|
Term
| which drug(s) is/are less effective wth distractability, has a longer onset of action, may exacerbate tics and should be monitored for rash? |
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Definition
|
|
Term
| Which TCAs are used in ADHD? |
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Definition
| Imipraime, Desimpramine, and to a lesser extent Nortriptyline |
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|
Term
| Which drug class is most dangerous if overdosed? |
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Definition
|
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Term
| Which drug(s) may have CV SEs and should be tapered when discontinuing? |
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Definition
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Term
| Which drug(s) should have ECG, vitals, behavior and compliance (by blood levels and irritable, agitated or cognitive issues if overmedicated) monitored? |
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Definition
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Term
| Which drugs are the a2 adrenergic agonists? |
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Definition
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Term
| The a2 adrenergic agonists are (more/less/equally as) effective compared to other agents. |
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Definition
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Term
| Which drug(s) is/are useful in comorbid OCD, depression, anxiety, tics, or enuresis? |
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Definition
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Term
| Which drugs are used as adjuncts for behavior, aggression and sleep? |
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Definition
| guanfacine and clonidine (the a2 agonists) |
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Term
| Compared to Clonidine, guanfacine has a (longer/shorter) t1/2 and is (less/more) selective |
|
Definition
| longer half life and more selective |
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|
Term
| Which drug(s) is/are contraindicated in depression? |
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Definition
|
|
Term
| which nonstimulant lacks childrens' studies? |
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Definition
|
|
Term
| Which a2 agonist is available as a patch? |
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Definition
|
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Term
| which drug(s) may cause rebound, is toxic if ingested and must watch for allergies? |
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Definition
|
|
Term
| Which drug(s) control(s) aggression and explosive behavior as well as impulsitivity? |
|
Definition
| Lithium and the anticonvulsants |
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|
Term
| Lithium and anticonvulsants are (effective/ineffective) in inattentive ADHD subtype children |
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Definition
|
|
Term
| What drug(s) may be used in childhood onset bipolar or ADHD-Bipolar disorder? |
|
Definition
| Lithium and the anticonvulsants |
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Term
| Which drug(s) is/are used for hyperactivity and impulsivity, but may cause negative effects on learning and EPS? |
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Definition
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|
Term
| Which drugs are used to control aggression in refractory patients? |
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Definition
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Term
| Which drug is most widely prescribed for tourette's to approve attention and behavior? |
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Definition
|
|
Term
| Clonidine (does/does not) change tic frequency |
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Definition
|
|
Term
| What are the atypical antipsychotics used for tourette's? |
|
Definition
| Risperidone especially, Ziprasidone, Aripiprazole (modest results w/ aripiprazole) |
|
|
Term
| What are the FDA approved tourette's drugs? |
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Definition
|
|
Term
| under what conditions should the doctor be notified with the stimulants? |
|
Definition
| tics develop or BP increases |
|
|
Term
| TCAs (should be avoided/are considered 1st line nonstimulants) |
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Definition
|
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Term
| Which drug(s) is/are used for bedwetting? |
|
Definition
| Desmopressin and imipramine |
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|
Term
| Which drug increases water reabsorption and reduces urine volume in the bladder? |
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Definition
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Term
| Desmopressin in the ______ dosage form should be avoided due to _______ |
|
Definition
| nasal spray; seizures resulting from hyponatremia |
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|
Term
| What is the next day concern when desmopressin wears off? |
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Definition
|
|
Term
| how often should drug holidays be given for the stimulants? Why are they given? |
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Definition
| 1-2 times/year to reasses the need and help with growth |
|
|
Term
| what would be the go-to ADHD drug for adults? |
|
Definition
| whatever was effective in childhood, if available |
|
|
Term
| which non-stimulant is not yet available as generic? |
|
Definition
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