Term
| What percentage of the dry human body is protein? |
|
Definition
|
|
Term
| What are the monomers for proteins? |
|
Definition
|
|
Term
| What type of protein is Immunoglobin G? |
|
Definition
|
|
Term
| How many amino acids is Immunoglobin made up of? |
|
Definition
|
|
Term
| What type of protein is a lysozyme? |
|
Definition
|
|
Term
| How many amino acids is lysozyme? |
|
Definition
|
|
Term
| How many structures of proteins are there? |
|
Definition
|
|
Term
| What is primary structure? |
|
Definition
| Chain of amino acids bonded together by peptide bonds |
|
|
Term
| What is secondary structure? |
|
Definition
| Hydrogen bonding between sections of the polypeptide chains. Forms beta-pleated sheets and alpha-helixes |
|
|
Term
| What are the two types of secondary structure? |
|
Definition
| Beta-pleated sheets and alpha-helixes |
|
|
Term
| What is tertiary structure? |
|
Definition
| Further folding by hydrophillic/hydrophobic interactions, disulphide bridges and ionic bonds |
|
|
Term
| What is quaternary structure? |
|
Definition
| Additions of prosthetic groups and combination of tertiary proteins |
|
|
Term
| What atom is at the N-terminus of an amino acid? |
|
Definition
|
|
Term
| What atom is at the C-terminus of an amino acid? |
|
Definition
|
|
Term
| What charge does the N-terminus of an amino acid have? |
|
Definition
|
|
Term
| What charge does the C-terminus of an amino acid have? |
|
Definition
|
|
Term
| What type of bond connects amino acids? |
|
Definition
|
|
Term
| What molecule is removed to form a peptide bond? |
|
Definition
|
|
Term
| Peptide bonds have what form of stereochemistry? |
|
Definition
|
|
Term
| Which stereochemical form of a peptide bond is more common? |
|
Definition
|
|
Term
| What makes the peptide bond rigid? |
|
Definition
| It ossiclates between being a single and a double bond |
|
|
Term
| What are Chloramphenicol and Penicillin? |
|
Definition
|
|
Term
| How does Chloramphenicol and Penicillin work? |
|
Definition
| Inhibit the building of peptide bonds in bacterial cell walls |
|
|
Term
| How many different amino acids are there? |
|
Definition
|
|
Term
| Which kind of amino acid optical isomer is natural? |
|
Definition
|
|
Term
| What happened when both optical isomers of 'Thalidomide' were put into a drug? |
|
Definition
| One prevented sickness in pregnancy, the other prevented limb development |
|
|
Term
| Negatively charged amino acids are usually what? |
|
Definition
|
|
Term
| Positively charged amino acids are usually what? |
|
Definition
|
|
Term
| Which amino acid has no optical isomerism? |
|
Definition
|
|
Term
| What is glycine used for in the human body? |
|
Definition
|
|
Term
| Which amino acid can form disulphide bridges? |
|
Definition
|
|
Term
| What are disulphide bridges used for in the body? |
|
Definition
| Increase stability in proteins outside the cell |
|
|
Term
| Give two examples of proteins that use disulphide bridges? |
|
Definition
|
|
Term
| Which amino acid acts as a base? |
|
Definition
|
|
Term
| How can the basisity of an amino acid be used in industry? |
|
Definition
| Can attract postive metal ions |
|
|
Term
| What is Phenylketoneuria? |
|
Definition
| Inability to breakdown excess phenylamine |
|
|
Term
| What percentage of a secondary proteins structure comes from hydrogen bonding? |
|
Definition
|
|
Term
| How are alpha-helixes formed? |
|
Definition
| Hydrogen bond between the oxygen on residue N and the hydrogen on residue N+4 |
|
|
Term
| In an alpha-helix how many residues per turn are they? |
|
Definition
|
|
Term
| Keratin is an example of a? |
|
Definition
|
|
Term
| How are alpha helixes related to DNA? |
|
Definition
| They can bind to DNA to control gene expression |
|
|
Term
| What are the two types of beta-pleated sheets? |
|
Definition
| Anti-parallel and parallel |
|
|
Term
| In a beta-pleated sheet how many degrees are there between residues? |
|
Definition
|
|
Term
| Name a beta-pleated sheet? |
|
Definition
|
|
Term
|
Definition
|
|
