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| The adult cochlea is formed by the ___ fetal month |
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| What is the scala media filled with? |
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| What are 4 common side effects of ototoxicity? |
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Definition
| Tinnitus, aural fullness, change in hearing sensitivity, and vertigo |
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Term
| What is the term for what the body does with a drug? |
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Definition
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| What is the term for what a drug does to the body? |
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| What clinical trial is when the drug or treatment is given to large groups of people to confirm its effectiveness, monitor side effects, compare it to commonly used treatments, and collect information that will allow the drug or treatment to be used safely? |
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| What is the clinical trail where researchers test a new drug or treatment in a small group of people for the first time to evaluate its safety, determine a safe dosage range, and identify side effects. |
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| What is the clinical trial where studies are done after the drug or treatment has been marketed to gather information on the drug’s effect in various populations and any side effects associated with long-term use. |
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| What is the clinical trial where the drug or treatment is given to a larger group of people to see if it is effective and to further evaluate its safety. |
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| "Acetaminophen" is an example of a.... |
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| N-(4-hydroxyphenyl)-acetamide is an example of.... |
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| Tylenol, liquiprin, tempra, tapanol are examples of the.... |
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Term
| What analogy has been used to describe the agonist, receptor, and drug-receptor complex? |
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Term
| The amount of a drug needed to produce 50% of a drug's potential max response is known as its... |
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Term
| ___ is the drug’s ability to elicit maximum response at a given dose; drug’s ability to treat a disease |
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Term
| Time it takes for a drug’s plasma concentration to decrease by 50% is known as.... |
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Term
| What are some complicating factors when considering drugs impact on the elderly? |
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Definition
| Differences in pharmokinetics, social isolation, poor nutrition, and reduced income |
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Term
| ___% of the elderly use over-the-counter medicaiton |
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Term
| True or False: Over time the proportion of a baby's body composed of fat increases and the proportion made up of water decreases |
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| True or False: Babies have slow or irregular peristalsis that may result in reduced absorption of a drug such that it may take longer for the medication to take effect |
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Term
Absorption in Children:
1. ___ absorption for intramuscular (IM) meds= much variation in circulation, Limited muscle mass, limited blood flow
2. .....absorption of oral meds
3. ___ absorption of topical meds |
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Definition
| Slower; Decreased or increased; Faster |
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Term
| True or false: children have mature livers at 6 months |
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Definition
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Term
| True or false: Kidneys mature at about 2 years of age. |
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Definition
| False. 4-12 months of age |
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Term
| True or false: "White-coat compliance" is adhering to drug regimen around medical appointments |
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Definition
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| True or false: Polypharmacy is concurrent use of many drugs; increases possibility for interaction between drugs |
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| True/false: The kidney actually gets larger with age |
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Definition
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| True/false: Drug-drug interactions refers to the negative effect of food that is eaten, preventing the desired effect of medication |
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Definition
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Term
| True/False: Karyorrhexis is when the nucleus condenses |
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Definition
| False-it is when it fragments |
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Term
| true/false: Cell necrosis is an active process. |
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Definition
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Term
| ___ is when the nucleus condenses |
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Definition
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Term
| ___ is the dissolution of a cell nucleus, especially during mitosis. |
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Definition
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Term
| True/false: it is always best to have a small therapeutic index |
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Definition
| False. You want a large one |
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Term
| True/false: Autolysis is when enzymes break down structures in cell after organ/organism dies; cell membrane stays intact but cytoplasm has vacuoles. |
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Definition
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Term
| ___ is a passive event; cell membrane & internal organelles are destroyed |
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Definition
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| ___ is a active process; cell shrinks & breaks into pieces; series of events is activated by enzymes |
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