Term
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Definition
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Term
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Definition
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Term
| smaller structures in ADHD? |
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Definition
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Term
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Definition
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Term
| SE of stimulants for ADHD? |
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Definition
| HA, insomnia, anorexia, stomachache, jitters (duh) |
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Term
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Definition
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Term
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Definition
| HA, abd pain, N, emotions |
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Term
| drugs for ADHD besides stims/stratera |
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Definition
| MAOi, SSRI, venlafaxine, buproprion, modafinil, a2ags |
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Term
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Definition
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Term
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Definition
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Term
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Definition
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Term
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Definition
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Term
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Definition
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Term
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Definition
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Term
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Definition
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Term
| where is the atrophy in bipolar |
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Definition
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Term
| where is the overgrowth in bipolar? |
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Definition
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Term
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Definition
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Term
| what happens to monoamine neurons in BP? |
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Definition
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Term
| major comorbidity w/ bipolar? |
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Definition
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Term
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Definition
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Term
| monozygotic twin concordance for bipolar? |
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Definition
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Term
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Definition
| blunted response to TSH, TRH, inc DA, dysregulation of 5HT and NE |
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Term
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Definition
| features of mania/depression |
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Term
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Definition
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Term
| what is rapid cycling BAD? |
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Definition
| more the 4 episodes of man/dep per year |
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Term
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Definition
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Term
| what is the big difference between BAD and the schizo disorders |
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Definition
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Term
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Definition
| prednisone, cimetidine, l-dopa/bromocriptine, baclofen |
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Term
| pharm therapy for mood stabilization in BAD |
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Definition
| Li, valproic acid, carbamazepine, gabapentin, oxcarbazapine, topiramate |
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Term
|
Definition
| setraline, fluoxetine, buproprion |
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Term
|
Definition
| risperidone, olanzapine, haldol |
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Term
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Definition
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Term
| "treatment of choice" for BAD |
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Definition
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Term
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Definition
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Term
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Definition
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Term
| 3 danger sx in mood disorder due to medical cause |
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Definition
| anhedonia, worthlessness, suicidal ideation |
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Term
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Definition
| rapid influx (like Na) w/ very slow efflux, inc DA/NE turnover, dec DAR sensitivity, inc turnover of phosphoinositol |
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Term
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Definition
| N+D, tremor, thirst (duh), conc, leukocytosis, weight gain, Epsteins, hThyroid, renal insuff, acne |
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Term
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Definition
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Term
| valproate and plasma proteins? |
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Definition
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Term
|
Definition
| drowsy, dizzy, diarrhea, tremor |
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Term
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Definition
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Term
| carbemazepine metabolism key fact |
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Definition
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Term
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Definition
| blocks Na channels, blocks Ca channels |
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Term
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Definition
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Term
| gen fxn of mesocortical path |
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Definition
| affect, emotion, cognition |
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Term
| gen fxn of mesolimbic path |
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Definition
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Term
| gen fxn of nigrostriatal path |
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Definition
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Term
|
Definition
| reversal of DA uptake, interference with DA into vesicle, MAOi |
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Term
|
Definition
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Term
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Definition
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Term
| 3 atypical antidepressants |
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Definition
| bup, mirtazapine, nefazadone |
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Term
| what receptor mediates NE induced 5HT release? |
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Definition
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|
Term
| in the limbic/cortex what does NE do to 5HT |
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Definition
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|
Term
| imipramine, amitriptyline |
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Definition
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Term
| tranylcypromine, phenelzine, moclobemide |
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Definition
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Term
|
Definition
| ortho hTN, cardiotox, confusion |
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Term
| why do TCAs have such serious SEs? |
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Definition
| they are not selective and also antagonize musc, hist, a1 |
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Term
| why can you try multiple SSRIs to get effectiveness? |
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Definition
| they are not "look-alikes" |
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Term
| what do SSRI do to P450 enzymes? |
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Definition
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|
Term
| what can SSRI do to sexual fxn |
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Definition
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Term
| what is unique about fluoxetine among the SSRIs? |
|
Definition
| long hl, active metabolite w/ long hl |
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Term
| two approved uses for Venlafaxine |
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Definition
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Term
|
Definition
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Term
|
Definition
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Term
| why does Bupropion have a "favorable" SE profile? |
|
Definition
| weight loss, no sex problems |
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Term
|
Definition
| a2 antag, 5HT2A,2C,3R antago |
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Term
|
Definition
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Term
|
Definition
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Term
|
Definition
| sedation, no problems with sex |
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Term
|
Definition
| diet (tyramine), SSRI (serotonin syndrom) |
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Term
|
Definition
| myoclonus, autonom, hyperreflexia, unstable BP, disorientation |
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Term
| why do ADs have a delayed onset? |
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Definition
| need to overcome "autoinhibitory receptors," neuroadaptive post-synaptic change |
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