Term
| A series potential fatal condition neuroleptic malignant syndrome (NMS) characterized by hypothermia, muscular rigidity, catatonia (patient appears frozen in position) and autonomic nervous system and ability is associated with the use of |
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Definition
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Term
| Gammaaminobutyric acid GABA |
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Definition
| An important inhibitory neurotransmitter that functions to keep out emotions and behavior under control |
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Term
| Unlike other three anti-psychotic drugs classes the anti-typical drugs is to activity more than they reduce the activity of dopamine |
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Definition
| For that reason they cause significantly lower levels of EPS |
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Term
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Definition
| More serious condition that they develop after long-term phenothiazine antipsychotic therapy. This condition involves involuntary movements of the lips, jaw, tongue, and extremities |
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Term
| Situations that bring about stress and anxiety, and a person will quickly result in |
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Definition
| The limbic system is involved with regulating of emotional behaviors and responses any emotionally anxiety producing situation increases the activity of the limbic system |
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Term
| Eventually the long active metabolites of long acting benzodiazepines are |
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Definition
| Are inactivated by being conjugated with glucuronic acid. This step and activates them and allows them to be excreted in urine |
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Term
| The main use of the extrapyramidal syndrome (EPS) |
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Definition
| Excessive blockade of dopamine D2 receptors. |
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Term
| What are the benefits the show side effects of phenothiazine antipsychotic drugs |
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Definition
| For the treatment of nausea and vomiting these side effects allow the phenothiazines to be used for treating pruritis certain allergic reactions. However, these actions also increase adverse drug reaction |
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Term
| The manic phase of manic-depressive personality disorder can be treated with which class of antipsychotic medication? |
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Definition
| The butyrophenones are high potency drugs that differ chemically from the phenothiazines, but that produce the same type of antipsychotic effects. The main drug of this group is Haloperidal (Haldol). Haloperidol is especially useful in the treatment of highly agitated and manic patient |
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Term
| Atypical drugs are associated with several metabolic disturbances such as |
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Definition
| Weight gain, evaluated triglyceride (hyperlipidemia), and development of diabetes mellitus |
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Term
| What are the side effects of the patient takin Clozapine and atypical antipsychotic drug |
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Definition
| More likely to develop an infection, higher indecency of sedation, seizures, weight gain, and agranulocytosis, lottery effects involved, decreased white blood cells, which may increase infection's and require WBC monitoring |
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Term
| A special formulation of Olanzapine an atypical antipsychotic is available for |
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Definition
| Difficult patients needing immediate treatment from a psychotic episode. In addition to regular tablets. There is a tablet formulated of Zyprexa (Zeyprexz zydis that rapidly dissolves in the mouth and an injectable pre-preparation for IM administration |
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Term
| One of the main characteristics of phenothiazine antipsychotic drugs refers to the basic chemical structure of large number of drugs somewhere and structure and pharmacological action |
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Definition
| These drugs block D2 receptors to a greater degree than they block five HT 2A receptors |
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Term
| Comment adverse effects of phenothiazine antipsychotics |
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Definition
| Such as dry mouth, constipation, visual disturbances, and sedation are due to the anticholinergic and antihistaminic action |
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Term
| Ways to alleviate parkinsonism which may develop from continuous use of phenothiazine: Parkinsonism involves development of muscular rigidity, tremors, and other disturbances of movement |
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Definition
| Reducing the dosage, stopping the drug, or administering centrally acting anti-chlorogenic drugs usually improves, these three were logical conditions |
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Term
| Symptoms of tardive dyskinesia often appear when |
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Definition
| Antipsychotic drug treatment is stopped the symptoms can be suppressed by reinstating the drug or by increasing the dose of an antipsychotic drug |
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Term
| unlike the phenothiazine,butyrophenone, and thioxanthene drugs |
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Definition
| The atypical antipsychotic drug effects and reduce the activity of the by the HT 2A receptors more than they interfere with the D2 receptors |
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Term
| thiothixene is a high potency antipsychotic medication that |
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Definition
| Associated with higher incidences of extra pyramidal syndrome EPS |
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Term
| With the exception of clozapine the atypical drugs do not cause |
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Definition
| Significant anti-cholinergic , alpha adreergic blocking or antihistaminic actions compared to some of the other drugs |
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Term
| Benzodiazepines rely on ligand gated chloride channels to achieve their effects of membrane hyper polarization |
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Definition
| Benzodiazepines, decreased the excitability on the functional activity of specific areas of the brain and spinal cord. GABA appears to allow more chloride ions to pass into the neuron, which makes it kind of the neuron or negatively charged (hyper polarization). hyperpolarization of the neuron reduces the neurological excitability and consequently reduces depressive effect on those neuron |
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