Term
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Definition
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Term
| somatotropin, recombinant |
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Definition
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Term
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Definition
| somatostatin analog 1. longer lasting than SS 2.more selective for GH, rather than insulin 3. uses: acute variceal bleeding, metastatic carcinoid tumor, VIP secreting tumor, acromegaly 4. note that the pharamcological t1/2 is less than biological t1/2 |
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Term
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Definition
| dopamine agonist uses: hyperprolactinemia, acromegaly, detrusor instability |
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Term
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Definition
| dopamine agonist uses: hyperprolactinermia, acromegaly, detrusor instability |
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Term
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Definition
| thyrotropin releasing hormone (TRH) uses: diagnostic tool only, if pituitary working, should see increase in TSH. If problem is with pituitary, no increase will be seen. t1/2 is very short (4m) |
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Term
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Definition
| synthetic GnRH uses: give pulsitile to induce ovulation, treat delayed puberty |
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Term
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Definition
| GnRH analog uses: constant admin causes down-regulation of receptors, causing decrease in FSH/LH. Use for precocious puberty, endometriosis, prostate cancer, infertility (can better control ovulation)
ROA: intranasal |
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Term
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Definition
| GnRH analog uses: constant admin causes down-regulation of receptors, causing decrease in FSH/LH. Use for precocious puberty, endometriosis, prostate cancer, infertility (can better control ovulation) |
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Term
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Definition
| GnRH analog uses: constant admin causes down-regulation of receptors, causing decrease in FSH/LH. Use for precocious puberty, endometriosis, prostate cancer, infertility (can better control ovulation) |
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Term
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Definition
| prototypical GnRH anatagonist advantages: prevents initial LH/FSH surge seen in GnRH analog therapy
uses: infertility |
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Term
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Definition
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Term
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Definition
| activity like LH (induce ovulation, stimulates corpus luteum, increase testosterone in males ROA: IM |
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Term
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Definition
| human menopausal gonadotropins FSH=LH activation ROA: IM |
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Term
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Definition
| decreases bone resorption; slows bone turnover, inhibits formation, growth and dissolution of crystals. Uses: osteoporosis, hypercalcemia |
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Term
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Definition
| Decreases bone resorption uses: Paget's, osteoporosis, hypercalcemia (hypervitaminosis D) |
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Term
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Definition
| increases bone formation, structure similar to PTH. -Once daily low dosing, stimulates osteoblasts without activating osteoclasts uses: hypercalcemia |
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Term
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Definition
| stimulates increased Ca2+ absorption from the distal tubule. uses: hypocalcemia |
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Term
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Definition
| promotes Ca uptake in GI uses: hyperparathyroidism, vit D deficiency, malabsorption. 10-14d lag time! |
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Term
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Definition
| Converted to Ca salt by HCl uses: treats mild hypocalcemia, maintenance therapy. |
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Term
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Definition
| Ca salt given i.v. DOC for severe hypocalcemia. careful with patients also on dig, can precipitate arrhythmias |
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Term
| furosemide (effects on Ca2+) |
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Definition
| promotes Ca excretion at loop of henle uses: hypercalcemia |
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Term
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Definition
| promote bone formation give p.o. uses: hypercalcemia |
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Term
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Definition
| Act as vit D anatagnoist (i.e., prevents Ca2+ absorption from gut) uses: hypercalcemia |
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