Term
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Definition
| A broad term for an ulcer occurring in the esophagus, stomach, or duodenum within the upper GI tract. |
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Term
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Definition
| Acid released from the parietal cells of the stomach that is influenced by histamine, gastrin, and acetylcholine. |
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Term
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Definition
| One of the main digestive enzymes produced in the stomach that breaks down proteins into smaller peptides. |
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Term
| Gastric mucosal barrier (GMB) |
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Definition
| A thick, viscous, mucous material that provides a barrier between the mucosal lining and acidic gastric secretions. |
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Term
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Definition
| An ulcer that results from reflux of acidic gastric secretions into the esophagus as a result of a defective or incompetent cardiac sphincter. |
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Term
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Definition
| An ulcer that frequently occurs because of a breakdown of the GMB. |
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Term
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Definition
| An ulcer caused by hypersecretion of acid from the stomach passing into the duodenum because of insufficient buffers to neutralize gastric acid in the stomach, a defective or incompetent pyloric sphincter, or hypermotility of the stomach. |
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Term
| Gastroesophageal reflux disease (GERD) |
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Definition
| An inflammation or erosion of the esophageal mucosa caused by a reflux of gastric acid content from the stomach into the esophagus. |
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Term
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Definition
| An ulcer that usually follows a critical situation such as extensive trauma or major surgery. |
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Term
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Definition
| Promote ulcer healing by neutralizing hydrochloric acid and reducing pepsin activity; they do no coat the ulcer. |
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Term
| Histamine 2 receptor blockers (antagonists) |
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Definition
| Popular drugs used in the treatment of gastric and duodenal ulcers. |
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Term
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Definition
| Ulcers are usually named according to the what? |
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Term
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Definition
| What is the most common type of peptic ulcer? |
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Term
| Hydrochloric acid and pepsin |
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Definition
| Peptic ulcers occur when there is a hypersecretion of what? (two things) |
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Term
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Definition
| Under normal conditions, the pH of the stomach varies from _____. |
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Term
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Definition
| What is activated in the stomach at a pH of 2? |
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Term
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Definition
| How long does it take for an ulcer to heal? |
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Term
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Definition
| What Gram-negative bacillus is linked to the development of peptic ulcers? |
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Term
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Definition
| H. Pylori is treated with _____. |
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Term
| MOC (metronidazole, omeprazole, and clarithromycin) |
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Definition
| What triple therapy is commonly used to treat peptic ulcers caused by H. pylori? |
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Term
| Incompetent lower esophageal sphincter |
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Definition
| What is the main cause of GERD? |
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Term
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Definition
| Antiulcer drug that has minimal effect in preventing and treating ulcers. |
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Term
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Definition
| PPIs suppress gastric acid secretion by inhibiting the hydrogen/potassium _____ enzyme. |
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