Term
| This is the transporter for the reuptake of ACh |
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Definition
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Term
| The enzyme that breaks down ACh |
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Definition
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Term
| Deficiency in this leads to memory loss associated with Alzheimer's Disease |
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Definition
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Term
| The part of the brain that experiences shrinkage in Alzheimer's Disease |
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Definition
| Temporal cortex/frontal lobe |
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Term
| There is a decreased release of this in Alzheimer's Disease |
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Definition
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Term
| Aphasia, apraxia, agnosia, disorientation, and impariment of memory are all symptoms of this disease |
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Definition
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Term
| Term that refers to a loss of language |
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Definition
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Term
| Term that refers to a loss of purposeful movements |
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Definition
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Term
| Term that refers to a loss of recognition of objects |
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Definition
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Term
| This amino acid transmitter is always excitatory |
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Definition
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Term
| This amino acid transmitter is always inhibitory |
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Definition
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Term
| The major excitatory transmitter in the brain |
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Definition
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Term
| Glutamate activates these receptors in the brain |
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Definition
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Term
| When glutamate activates NMDA receptors, it allows the entry of these ions |
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Definition
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Term
| Current drugs are effective in this percentage of epilepsy patients |
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Definition
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Term
| This type of seizure begins locally and remains localised |
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Definition
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Term
| This symptoms of this type of seizure include motor signs, sensory symptoms, and autonomic symptoms |
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Definition
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Term
| This symptoms of this type of seizure include impaired consciousness, various clinical manifestations depending on origin and spread |
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Definition
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Term
| This symptoms of this type of seizure include strong contractions of musculature and involuntary vocalisations |
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Definition
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Term
| This symptoms of this type of seizure include stopping current action and staring blankly, with little or no motor disturbance, abrupt recovery |
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Definition
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Term
| The most common type of epilepsy associated with complex partial seizures |
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Definition
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Term
| This type of seizure involves the whole brain and always a loss of consiousness |
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Definition
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Term
| Tonic-clonic and absence/petit-mal seizures are subtypes of this form of seizure |
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Definition
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Term
| This type of seizure is common in children |
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Definition
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Term
| Is acquired or genetic epilepsy more common? |
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Definition
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Term
| The effect we get from enhancing GABA |
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Definition
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Term
| The enzyme that metabolises GABA |
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Definition
| GABA transaminase (GABA-T) |
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Term
| These two types of drugs can bind to other sites on the GABA receptor ti increase inhibition |
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Definition
| Benzodiazepines and barbiturates |
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Term
| Do benzodiazepines and barbiturates modulate or activate the receptor? |
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Definition
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Term
| The way in which benzodiazepines and barbiturates activate the GABA receptor |
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Definition
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Term
| Diazepam and phenobarbitone are examples of this |
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Definition
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Term
| After one seizure, this percentage of people will have another |
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Definition
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Term
| The ion that is moving when an AP is starting |
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Definition
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Term
| Some epileptic drugs target Na channels on these types of neurons |
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Definition
| Those firing at a high frequency |
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Term
| The term that refers to prolonged and uncontrolled repeated seizures with a high morbidity and mortality |
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Definition
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Term
| Absence seizures are associated with these types of channels |
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Definition
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Term
| Are T-type Ca2+ channels low or high voltage activated? |
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Definition
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Term
| T-type Ca2+ channels within this area of the brain provide a "pacemaker" current that produces bursting intrinsic firing leading to absence seizures |
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Definition
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Term
| Some (but not the majority) of partial seizures are associated with this type of channel |
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Definition
| High voltage activated (HVA) Ca2+ |
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Term
| Gabapentin targets this type of channel |
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Definition
| High voltage activated (HVA) Ca2+ |
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Term
| Most anti-epileptic drugs have these as SEs |
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Definition
| Sedation, confusion, skin rashes |
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Term
| The use of this anti-epileptic drug is associated with a narrow safety margin |
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Definition
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Term
| Is a P450 enhancer or inhibitor increase the clearance and decrease the steady state levels of other interacting drugs |
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Definition
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Term
| Is a P450 enhancer or inhibitor decrease the clearance and increase the steady state levels of other interacting drugs |
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Definition
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