Term
| insulins produced w recombinant DNa technology with identical AA sequence to human insulin. |
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Definition
| regular insulins: humalin & novolin |
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Term
|
Definition
1. humalog
2. novolog
3. Apidra
4. lantus
5. levemir |
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Term
|
Definition
1. humalog
2. novolog
3. apidra |
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Term
| short to intermediate acting insulins: |
|
Definition
1. regular
2. NPH
both are novalin & humalin |
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Term
|
Definition
|
|
Term
| insulins: time of onset = 15-30minutes |
|
Definition
1. humalog
2. novalog
3. apidra |
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Term
| insulin: time of onset 30-60min |
|
Definition
| regular insulin (novolin/humalin) |
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Term
| insulin: time of onset 2-4hrs |
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Definition
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Term
| insulin: time of onset 4-5hrs |
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Definition
|
|
Term
| insulin: time of onset and effective duration is unknown |
|
Definition
|
|
Term
|
Definition
1. humalog
2. novolog
3. apidra |
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|
Term
|
Definition
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|
Term
|
Definition
|
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Term
|
Definition
|
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Term
|
Definition
|
|
Term
| insulin: effective duration 2-3hrs |
|
Definition
1. humalog
2. novolog
3. apidra |
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|
Term
| insulin: effective duration 3-6hrs |
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Definition
|
|
Term
| insulin: effective duration 8-12hrs |
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Definition
|
|
Term
| insulin: effective duration unkown: |
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Definition
|
|
Term
| insulin: effective duration 22-24hrs |
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Definition
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|
Term
| insulin dosing for adult w T1DM in units/kg/day |
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Definition
|
|
Term
| children with T1DM: insulin dosing in units/kg/d |
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Definition
|
|
Term
| insulin dosing for adolescents in units/kg/day |
|
Definition
| 1.0 to 1.5 units/kg/d during puberty until they reach adulthood |
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Term
| basal insulin should comprise what % of the total daily insulin dose> |
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Definition
|
|
Term
| bolus insulin should comprise what % of total daily insulin dose? |
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Definition
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|
Term
| if weight based dosing needs adjustment, what increments of units should insulin be changed? |
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Definition
| 1-2untis no more than 10%of total daily dose |
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|
Term
| in an insulin sensative preson (T1DM) 1 unit of insulin will decrease BG by: |
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Definition
|
|
Term
| insulin adjustments can be made every __to __ days IF pt routine is stable: |
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Definition
|
|
Term
| define intensive insulin therapy: |
|
Definition
| 3-4inj per day; basal insulin + bolus insulin - recommended for T1DM |
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|
Term
| one unit of insulin will cover __g of carbs: |
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Definition
|
|
Term
| 70kg adult insulin dose in units/day |
|
Definition
| 35-70units/day.... begin w 36units |
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|
Term
| recommended carb intake for breakfast, lunch, supper and snack: |
|
Definition
breakfast: 60g
lunch: 75g
supper: 75g
snack: 15-30g |
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Term
|
Definition
| daily NPH x0.8 = lantus dose (give lantus at bedtime) |
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|
Term
|
Definition
| normal physiologic rise in BG during awakening |
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Term
|
Definition
| hyperactive hyperglycemia in response to nocturnal hypoglycemia. BG near normal at bedtime and elevated upon awakening. have them take a 3am BG to distinguish btwn dawn phenom |
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|
Term
| describe mild hypoglycemia: |
|
Definition
| BG<60, adrenergic effects(anxiety sweating, tremor, tachy, hunger) |
|
|
Term
|
Definition
| oral ingestion on 10-15g carb resolve in 10-15min |
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|
Term
| describe moderate hypoglycemia: |
|
Definition
| adrenergic sx + neuroglycopenic sx (HA, irritable, confused, slurred speech) |
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|
Term
| moderate hypoglycemia tx: |
|
Definition
| 2 doses of 10-15g of carbs |
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|
Term
| describe severe hypoglycemia: |
|
Definition
| unresponsive, unconsious, convulsions. |
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|
Term
|
Definition
| emergency IV dextrose or IM glucagon |
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|
Term
| what is a GlucaGen Hypokit? |
|
Definition
| glucagon for emergency injection |
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|
Term
| what is extendbar/nitebite: |
|
Definition
| tiem released glucose bar to prevent nocturnal hypoglycemia |
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|
Term
|
Definition
| synthetic anylin: amylin is screted with insulin, slows gastric emptying and inhibits glucagon secretions |
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|
Term
| indications for pramlintide: |
|
Definition
| adjunct tx for T1&T2DM who have not achieved control with insulin; A1c<9% higher indicates increased insulin needed |
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|
Term
|
Definition
| initially 60mcg injected before meals increase to 120mcg when there is no nausea assoc w dose. |
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|
Term
| adjustment of insulin upon pramlintide initiation: |
|
Definition
1. decrease insulin 25% when A1c>8%
2. decr insulin 25-50% when A1c<8%
3. reduce total dose of premix insulin by 25% |
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|
Term
| 2 adverse affects of pramlintide: |
|
Definition
1. Hypoglycemia
2. GI (N/V,anorexia,early satiety) |
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