Term
| What are the SE of Griseofulvin? |
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Definition
| HA, GI Upset, Allergic Rxtns, hepatitis |
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Term
| Which drug is used to treat cryptococcal meningitis? |
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Definition
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Term
| What are the SE of Fluconazole? |
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Definition
| Mild GI upset, abnormal liver enzymes, fever, chills |
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Term
| How does fluconazole affect the CYP-450 system? |
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Definition
| inhibits the CYP-450 system leading to increased serum levels of several drugs including cyclosporine, warfarin, phenytoin and histamine antagonists |
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Term
| Which drugs are similar to Fluconazole? |
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Definition
| Itraconazole, voriconazole |
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Term
| Which anti-fungal can cause a SE of gynectomastia, decreased libido or menstrual irregularities due to its hormonal synthesis inhibition? |
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Definition
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Term
| Which anti-fungal can be used to treat Cushing's syndrome? |
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Definition
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Term
| Which anti-fungal can be used to treat cutaneous fungal infections (vulvovaginal candidiasis, tinea cruris and tinea pedis)? |
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Definition
| Miconazole and Clotrimazole |
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Term
| What are the SE of Flucytosine? |
|
Definition
| Bone Marrow Suppression and hepatotoxicity |
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Term
| What drug is used to treat oral and cutaneous candidiasis? |
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Definition
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Term
| What are the major SE of Amphotericin B? |
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Definition
| Nephrotoxicity, Infusion related reaction (fever, chills, muscle spasms, HA), abnormal LFTs |
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Term
| A 43 y/o female diabetic pt presents with c/o white, itchy vaginal discharge. On physical exam you note a cottage-cheese like appearance to the d/c. What med should you prescribe to this pt? |
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Definition
| Miconazole vaginal suppository (OTC Monistat) |
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Term
| A chemotherapy pt is admitted to the hospital with signs and symptoms of meningitis. A culture of the CSF fluid shows Cryptococcus. What is the first-line treatment for this condition? If the pts condition does not improve what other med can be added to the regimen? |
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Definition
Intrathecal infusion of Amphotericin B
Flucytosine can be added |
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Term
| A 43 y/o AIDS pt reports to the clinic with a fever, and is hypotensive. On PE there are creamy white plaques on the pts tongue and upper palate. What is your diagnosis and how should you treat it? |
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Definition
| Oral Candidiasis; treat with Fluconazole or Oral Nystatin |
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Term
| A 6 y/o girl presents with a patchy loss of hair x 1 week, without any systemic symptoms.On PE you find several ring-shaped lesions with raised papules along its rim and notable alopecia near the rim. There is no sign of inflammation and the pt does not complain of puritis. What treatment should be started? |
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Definition
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