Term
| What is the main clinical use of stimulants (amohetamines)? |
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Definition
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Term
| What Sx of ADHD do stimulants treat? |
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Definition
| core Sx: impulsivity, inattention, & motor restlessness |
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Term
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Definition
6+ Sx (from A or B) present for 6+ months to a point that is disruptive & inappropriate for developmental level
A) List of inattention Sx
B) List of Hyperactive/inpulsive Sx |
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Term
| How effective are stimulants are Tx of ADHD? |
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Definition
| so much so that combined CBT is not needed |
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Term
| What are the 5 amphetamines? |
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Definition
1) Amphetamine
2) DA
3) Methamphetamine
4) Methylphenidate
5) Dextroamphetamine |
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Term
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Definition
| release monoamines thru non-exocytotic mechanism |
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Term
| What form of stimulants have been developed for stable effect throughout the day? |
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Definition
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Term
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Definition
1) ADHD
2) excessive daytime sleepiness (narcolepsy, sleep apnea, etc)
3) appetite suppressants (historically) |
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Term
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Definition
headaches that are:
1) unilateral
2) pulsatile/throbbing
3) associated with N/V
4) sufficient intensity to interrupt daily activities
5) last 4-72 hrs if untreated |
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Term
| Who is affected by migranes? |
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Definition
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Term
| What tends to be the triggers for mirgranes? |
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Definition
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Term
|
Definition
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Term
Tx
migranes
(not severe, no vomiting) |
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Definition
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Term
|
Definition
1) Triptans
2) Dihydroergotamine |
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Term
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Definition
| 5-HT1B/1D receptor agonists => inhibition of neurotransmitter release |
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Term
| When in combination with what do triptans seen to be most effective in treating migranes? |
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Definition
| NSAIDs (may be given in combination with antiemetics as well) |
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Term
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Definition
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Term
| When in the migrane course should triptans be administered? |
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Definition
| as early as possible (early intervention is important) |
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Term
| Why shouldn't triptans be given as monotherapy? |
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Definition
| Alone, not much better than NSAIDs & have a high cost |
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Term
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Definition
1) sumatriptan
2) fovatriptan |
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Term
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Definition
1) β blockers (propanolol, timolol, metoprolol)
2) AED (valproate, topiramate)
3) TCAs
4) Behavioral therapies |
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Term
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Definition
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