Term
|
Definition
| blocks transporter preventing uptake |
|
|
Term
|
Definition
| blocks the AChH+ transporter, prevents efficient release |
|
|
Term
|
Definition
| degrades synaptobrevin preventing synaptic vesicle fusion |
|
|
Term
|
Definition
| short acting, diagnostic purposes |
|
|
Term
|
Definition
| myasthenia gravis, colinergic agonist at Nm receptors |
|
|
Term
|
Definition
| preferred myasthenia gravis treatment |
|
|
Term
|
Definition
|
|
Term
|
Definition
| Myasthenia gravis, antidote |
|
|
Term
| Acetylcholinesterase inhibitors |
|
Definition
Edrophonium, Neostigmine, pyridostigmine, ambenonium, physostigmine.
Diisopropyl fluorophosphate.
Tacrine, Donepezil, Rivastigmine, Galantamine. |
|
|
Term
| Diisopropyl fluorophosphate |
|
Definition
| toxin, organophosphate insecticide |
|
|
Term
|
Definition
| Alsheimer's disease, liver tests must be normal |
|
|
Term
|
Definition
|
|
Term
|
Definition
| Alsheimer's, both acetylcholinesterase and butyrylcholinesterase by carbamoylate complex |
|
|
Term
|
Definition
| Alzheimer's, also non-potentiating ligand of nicotinic receptors |
|
|
Term
| Muscarinic Receptor Agonists |
|
Definition
Methachline.
Carbachol, Bethanechol, Civimeline, Pilocarpine. |
|
|
Term
|
Definition
| Diagnosis of asthema. Avoid with cardiovascular concerns. Selective for cardiovascular muscarinic cholinergic receptors |
|
|
Term
|
Definition
| Glaucoma, enhanced nicotinic action relative to other choline esters. Cannot be used systemically. Miosis/ decreased pressure |
|
|
Term
|
Definition
| Urinary tract motilityalmost completely selective for muscarinic receptors |
|
|
Term
|
Definition
| Xerostomia in Sjogren's syndrome, M1 and M3 |
|
|
Term
|
Definition
| Xerostomia in Sjogren's syndrome |
|
|
Term
| Nicotinic Receptor Agonists |
|
Definition
|
|
Term
|
Definition
Induction of neuromuscular blockade. causes bradyarrhythmia, rhabdomyolysis, respiratory depression.
Malignant hyperthermia contraindicated, transient fasciculations |
|
|
Term
| Muscarinic Receptor Antagonists |
|
Definition
Atropine.
Scopolamine.
Pirenzepine, Methscopolamine, Glycopyrrolate.
Ipratropium, Tiotropium.
ovybutunin, Propantheline, Terodiline, Tolterodine, Trospium, Darifenacin, Solifenacin. |
|
|
Term
| Nonspecific muscarinic receptor antagonists |
|
Definition
| Oxybutunin, propantheline, tolterodine, trospium |
|
|
Term
| Selective M3 receptor antagonists |
|
Definition
| darifenacin and solifenacin |
|
|
Term
|
Definition
| Avoid with narrow-angle glaucoma: Oxybutunin, Propantheline, Terodiline, Tolterodine, Trospium, darifenacin, Solifenacin |
|
|
Term
| Nicotinic Receptor Antagonists |
|
Definition
Pancuronium, Tubocurarine, Vencuronium, Rocuronium, Mivacurium.
Trimethaphan, Mecamylamine. |
|
|
Term
| Pancuronium, Tubocurarine |
|
Definition
| Nicotinic Receptor Antagonist, long acting |
|
|
Term
| Vecuronium and Rocuronium |
|
Definition
| Nicotinic Receptor Antagonist, intermediate acting |
|
|
Term
|
Definition
| Nicotinic Receptor Antagonist, short-acting agent, causes salivation and flushing |
|
|
Term
| Trimethaphan and Mecamylamine |
|
Definition
| Acute Aortic dissection, causes paralytic ileus and urinary retention, and syncope. Cause ganglionic blockade |
|
|
Term
|
Definition
| Contraindications: asphyxia, respiratory insufficiency, neonates |
|
|
Term
|
Definition
| coronoary insufficiency, glaucoma, MI, pyloric stenosis, renal insufficiency, sulfonamides |
|
|
