Term
|
Definition
| inhibits Cox1 and Cox2 (IRREVERSIBLE) |
|
|
Term
|
Definition
| Pain, headache, myalgia, prophlyaxis for stroke and MI |
|
|
Term
|
Definition
| GI bleed, Reye's syndrome, worsing asthma, angioedema, ringing ears, GI issues |
|
|
Term
| Ibuprofen, Piroxicam, Nabumetone, Proxicam, MOA |
|
Definition
| Inhibit Cox1/2 reversibly |
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
| long plasma half life and 20 times more potent than aspirin |
|
|
Term
|
Definition
| close patent ductus arteriosus |
|
|
Term
|
Definition
|
|
Term
|
Definition
| blocks Cox-2 more than Cox-1 less GI issues |
|
|
Term
|
Definition
| weak COX inhibitor may have greater effect in CNS |
|
|
Term
|
Definition
|
|
Term
|
Definition
| hepatotoxicity, rash, hypothermia, |
|
|
Term
| Antidote for acetaminophen overdose |
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
| OA, RA, spondylitis, dysmenorrhea, Pain FAP |
|
|
Term
|
Definition
| MI, Stroke, HF, Gi bleed, worse asthma, edema |
|
|
Term
|
Definition
|
|
Term
|
Definition
| Keep open patent ductus arteriosus/ ED |
|
|
Term
|
Definition
| PGE1 analog with vasodilator properties |
|
|
Term
|
Definition
| Abortion with mifepristone, Protect GI in NSAIDS use |
|
|
Term
|
Definition
| Rare Anemia, Arrythmia, GI issues |
|
|
Term
|
Definition
| PGF alpha2 analogue stimulate uterine contraction |
|
|
Term
|
Definition
| Abortion in 2nd semester, postpartum hemmorhage |
|
|
Term
|
Definition
| dystoniam pulm edema, GI diarrhea, Fever |
|
|
Term
| Latanoprost, Bimatoprost, Travoprost MOA |
|
Definition
| PGF alpha 2 analogue, vasodilator |
|
|
Term
| Latanoprost, Bimatorpost, Travoprost TX |
|
Definition
| Ocular hypertension, Open angle glaucoma |
|
|
Term
|
Definition
| Prostacyclin analogue that stumulates pulmonary vasodilation |
|
|
Term
|
Definition
|
|
Term
| Dazoxiben, Pirmagrel, MOA |
|
Definition
| inhibit TXA2 synthesis by blocking thromboxane synthase |
|
|
Term
|
Definition
| thromboxane A2 receptor Antagonist |
|
|
Term
|
Definition
| thromboxane A2 receptor Antagonist |
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
| Montelukast, Zafirlukast MOA |
|
Definition
| antagonist of Lueckotrine type 1 receptor |
|
|
Term
| Montelulast, Zafirlukast TX |
|
Definition
| Asthma, allregic rhinitis |
|
|
Term
| Montelulast, Zafirlukast AE |
|
Definition
| allergic angitis, hepatitis, GI, hallucinations, agitation |
|
|
Term
|
Definition
| Tx RA by antagonist of IL-1 receptor |
|
|
Term
|
Definition
|
|
Term
| Infliximab, adalimumab, golimumab |
|
Definition
|
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