Term
| What affect do Vitamin D metabolites/analogs have on immunity? |
|
Definition
| promote innate immunity, inhibit adaptive immunity |
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Term
| How do the half lives of Vit D preparations compare to the metabolites and analogs? |
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Definition
|
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Term
| Bisphosphonates ("-dronate")- MOA? |
|
Definition
| suppress the activity of osteoclasts in part via inhibition of farnesyl pyrophosphate synthesis |
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Term
| Which drugs suppress the activity of osteoclasts in part via inhibition of farnesyl pyrophosphate synthesis? |
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Definition
|
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Term
| what are the effects of bisphosphonates? |
|
Definition
| inhibit bone resorption and secondarily bone formation |
|
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Term
| Which drugs inhibit bone resorption and secondarily bone formation? |
|
Definition
|
|
Term
| Applications of bisphosphonates? |
|
Definition
| osteoporosis, bone mets, hypercalcemia |
|
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Term
|
Definition
| adynamic bone, possible renal failure, rare osteonecrosis of the jaw |
|
|
Term
| MOA of teriparatide and calcitonin? |
|
Definition
| these hormones act on their receptors coupled to G protein signaling pathways |
|
|
Term
| Which drugs are hormones that act on their receptors coupled to G protein signaling pathways? |
|
Definition
| teriparatide and calcitonin |
|
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Term
|
Definition
|
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Term
| Which drug stimulates bone turnover? |
|
Definition
|
|
Term
|
Definition
| suppresses bone resorption |
|
|
Term
| Which drug is a hormone that suppresses bone resorption? |
|
Definition
|
|
Term
| Usage of teriperitide and calcitonin? |
|
Definition
| both are used in osteoporosis, calcitonin is used for hypercalcemia |
|
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Term
|
Definition
| ma cause hypercalcemia and hypercalciuria |
|
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Term
|
Definition
| inhibits bone resorption without stimulating breast or uterus |
|
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Term
| Does raloxifene prevent hot flashes? It is associated with increased risk of what? |
|
Definition
|
|
Term
| Which drug is associated with increased risk of thrombophlebitis? |
|
Definition
|
|
Term
|
Definition
| activates calcium sensing receptor |
|
|
Term
| Which drug actives the calcium sensing receptor? |
|
Definition
|
|
Term
| Applications of cinacalcet? |
|
Definition
|
|
Term
| which drug is basically only used in hyperparathyroidism? |
|
Definition
|
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Term
|
Definition
|
|
Term
| which drug is associated with nausea? |
|
Definition
|
|
Term
| Minerals - calcium, phosphate, strontium - effects? |
|
Definition
| strontium suppresses bone resorption and increases bone formation, the others are required for bone mineralization |
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Term
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Definition
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