Term
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Definition
| Decr atrial contractility, bronchoconstriction, intestinal contraction, rapid/short vasodilation |
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Term
| What type of vasodilation occurs at the H1 receptor? |
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Definition
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Term
| Where does Diphenhydramine act and what is it action? |
|
Definition
| Competitive Antagonist @ H1 |
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Term
| What histamine receptor antagonist would be used to treat hay fever or motion sickness? Which receptor does this act on? |
|
Definition
| Diphenhydramine (benadryl), H1 |
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Term
| A competitive antagonist of H1 has what AEs? |
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Definition
| Anti-muscarinic (CNS depression, bradycardia), orthostatic hypotension |
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Term
| What is the benefit of using a 2nd generation H1 antagonist over a 1st generation? |
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Definition
| Non-sedating = Fexofenadine (allegra) vs Diphenhydramine (benadryl) |
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