Term
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Definition
| due to dysfunction of the target gland |
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Term
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Definition
| due to dysfunction of the pituitary gland |
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Term
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Definition
| results from hypothalamus disorder |
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Term
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Definition
| disease of posterior pituitary, kidneys produce abnormally large volumes of dilute urine |
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Term
| Neurogenic Diabetes Insipidus |
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Definition
| lack of ADH; could be due to tumor of posterior pituitary, trauma, genetic, 50% idiopathic. TX- Vasopressin:DDAVP |
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Term
| Nephrogenic Diabetes Insipidus |
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Definition
| inability of kidneys to respond to ADH; can be drug induced or genetic. TX - eliminate the drug or disease causing the problem |
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Term
| Psychogenic Diabetes Insipidus |
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Definition
| ADH is suppressed by excessive fluid intake; due to abnormality in brain cells that regulate thirst. TX - psychiatric intervention, DDAVP |
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Term
| Gestational Diabetes Insipidus |
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Definition
| ADH insufficiency; the placenta destroys the hormone. This resolves within 4-6 weeks of delivery |
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Term
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Definition
| thirst with polydipsia, polyuria, and nocturia. |
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Term
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Definition
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Term
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Definition
| excretion of abnormally large quantities of urine (in normal person the average is 1500 ml/day, in DI they excrete around 4-6L/day) |
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Term
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Definition
| excessive urination at night |
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Term
| Growth Hormone Deficiency |
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Definition
| in children this deficiency interferes with linear bone growth, resulting in symmetrical dwarfism. Normal intelligence, short stature, immature facial features, delayed puberty |
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Term
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Definition
| Excess growth hormone, occurs before the fusion of epiphyses of long bones, leads to symmetrical growth in children |
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Term
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Definition
| Can be a causative factor for Gigantism, a benign tumor arising from growth hormone results in hypersecretion of GH |
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Term
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Definition
| Growth hormone excess in adults, after bones are done growing, leads to asymmetric growth of the soft tissues. mostly from pituitary adenoma |
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Term
| Tests of Thyroid Function |
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Definition
| TSH - determine if problem is primary (thyroid gland) or secondary (pituitary). Free T4 measures unbound T4 free to enter cells |
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Term
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Definition
| weight loss, increased appetite, heat intolerance, thin fine hair, goiter |
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Term
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Definition
| autoimmune, increased thyroid hormone production, goiter, women>men |
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Term
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Definition
| weight gain, fatigue, cold intolerance, constipation, coarse hair |
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Term
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Definition
| congenital hypothyroidism,hormone replacement begins within first 6 weeks of life |
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Term
| Replacement of thyroid hormone for hypothyroidism |
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Definition
| synthetic T4 (Synthroid), monitor patient's TSH levels |
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Term
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Definition
| release of glucocorticols (cortisol), mineralcorticoids (aldosterone) and androgens and estrogens (sugar/salt/sex) |
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Term
| Regulation of cortisol secretion |
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Definition
| based on normal sleep schedule, levels peak in the early morning |
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Term
| Signs of Cushing Syndrome |
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Definition
| central obesity, moon facies, easy bruising, poor wound healing, striae, increased body and facial hair |
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Term
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Definition
| excessive anterior pituitary secretion of ACTH |
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Term
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Definition
| excessive level of cortisol, regardless of the cause. Can be from tumor, cancer, or iatrogenic (too much prednisone over time) |
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Term
| Treatment of Cushing Syndrome |
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Definition
| Surgery if a tumor, if on extra steroids should wean off gradually (so your body can become used to making them again) |
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