Term
| Potent cytokines that possess antiviral, immunomodulating, and antiproliferative actions. |
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Definition
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Term
| Recombinant interferons alpha-2a and alpha-2b are used in... |
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Definition
hairy cell leukemia
Kaposi's sarcoma |
|
|
Term
| What is interferon alpha-2b used in? |
|
Definition
malignant melanoma
follicular leukemia |
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Term
| What agent appears to restore depressed immune function of B cells, T cells, monocytes and macrophages? |
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Definition
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Term
| What is the only clinical indication of levamisol? |
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Definition
| Dukes' stage C colon cancer |
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Term
| What agent is a sedative, hypnotic and anti-inflammatory drug? |
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Definition
|
|
Term
| What is thalidomide approved for? |
|
Definition
skin conditions associated with leprosy
newly diagnosed multiple myeloma |
|
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Term
| What drug is an immunomodulatory agent indicated in patients with transfusion-dependent anemia due to myelodysplastic syndrome? |
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Definition
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|
Term
| Aldesleukin is also known as... |
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Definition
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Term
| What agent induces and expands a T-cell response cytolytic for tumor cells? |
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Definition
|
|
Term
| What is aldesleukin approved for? |
|
Definition
| metastatic renal cell carcinoma |
|
|
Term
| What agent is a fusion protein composed of diphtheria toxin fragments A and B and the receptor-binding portion of interleukin-2? |
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Definition
|
|
Term
| What is denileukin diftitox approved for? |
|
Definition
| cutaneous T-cell lymphoma |
|
|
Term
| What preparation is indicated in the treatment and prophylaxis of carcinoma in situ of the urinary bladder? |
|
Definition
| Bacillus Calmette-Guerin (BCG) |
|
|
Term
| What vaccine is approved for the treatment of asymptomatic or minimally symptomatic androgen-independent prostate cancer? |
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Definition
|
|
Term
| Indication of Alemtuzumab |
|
Definition
| B-cell chromic lymphocytic leukemia |
|
|
Term
| Indication of Bevacizumab |
|
Definition
| Advanced colorectal cancer |
|
|
Term
|
Definition
Advanced colorectal cancer
Squamous cell carcinoma of the head and neck |
|
|
Term
|
Definition
|
|
Term
| Indication of Ibritumomab |
|
Definition
|
|
Term
|
Definition
| Chronic lymphocytic leukemia |
|
|
Term
| Indication of Panitumumab |
|
Definition
| Metastatic colorectal cancer |
|
|
Term
|
Definition
Non-Hodgkins lymphoma
Rheumatoid arthritis |
|
|
Term
| Indication of Tositumomab |
|
Definition
|
|
Term
| Indication of Trastuzumab |
|
Definition
Metastatic breast cancer
Gastric cancer |
|
|
Term
| What drugs are capable of reversing loss of specialization? |
|
Definition
|
|
Term
| What is one of the major retinoids? |
|
Definition
|
|
Term
| The biological activities of retinoids are mediated through specific nuclear... |
|
Definition
| retinoic acid receptors and retinoid X receptors |
|
|
Term
| What type of leukemia involves a translocation of the Retinoic Acid Receptor-alpha gene from chromosome 15 to chromosome 17? |
|
Definition
| Acute promyelocytic leukemia |
|
|
Term
| What reverses the chromosomal translocation of Retinoic Acid Receptor-alpha? |
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Definition
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|
Term
| What rexinoid is indicated in the treatment of the cutaneous manifestations of cutaneous T-cell lymphoma? |
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Definition
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