Term
First Stage of Prevention:
Goal? Intervention? |
|
Definition
Primary
Reduce risk factors.
Nutrition, Exercies, Monitoring of envirmental risks, prevention and educational programs |
|
|
Term
Second Stage of Prevention?
Goals? Interventions? |
|
Definition
Secondary.
Early detection, early intervention, inhibit proliferations.
Regular Exercise, self-examination, early medical treatment, sports physicals. |
|
|
Term
Third Stage of Prevention?
Goals? Interventions? |
|
Definition
Tertiary.
Limit established diesase.
Medcial treatment, supportive and restorative. |
|
|
Term
|
Definition
| the molecular site where the drug has a significant chemical interaction to produce a biological effect. |
|
|
Term
|
Definition
| the time it takes for the concentrated drug molecule at the site of action to become large enough to cause a noticable biological response |
|
|
Term
|
Definition
a comparison of the amount and rate of drug entering the general circulation for two or more simular formulations for the same drug.
If the bioavailability of the drug is equal, they are bioequivilant. |
|
|
Term
|
Definition
the same clinical response when two products are compared.
Its determined by the bioavailibilty of the drug. if they are therapeutically equivilant, they are bioequivilant. |
|
|
Term
|
Definition
| the space in the body that is available to the drug. |
|
|
Term
|
Definition
| when the drug penetrates the membrane due to solubility of the drug in the membrane. |
|
|
Term
|
Definition
| a binding site where the protien transports the compound. |
|
|
Term
| Routes of administration: |
|
Definition
Oral
Sublingual and buccal
parenteral
topical
inhalation
Rectal |
|
|
Term
|
Definition
| the study of the impact of drugs on the body |
|
|
Term
|
Definition
| the response of two or more drugs on the body. The same effect, nothing additional |
|
|
Term
|
Definition
| getting a greater response from the drugs used together that would be expected. |
|
|
Term
|
Definition
| the second drug reduces the effect of the first drug |
|
|
Term
|
Definition
| diminished response to a drug as a result of continuous use. |
|
|
Term
|
Definition
| the ability of the drug to chemically bind with the receptor |
|
|
Term
|
Definition
| the ability of the drug to either initiate or prevent a biological response |
|
|
Term
| dose -response principle: |
|
Definition
| as the concentration of the drug increases, the more drug molecule will occupy mroe receptors in the body which will produce a greater response in the body |
|
|
Term
|
Definition
| used to compare the dose of a drug required to produce a particular effect relative to the dose of another drug that acts by a similar mechanism to produce the same effect. |
|
|
Term
|
Definition
| the effective dose of a drug produced in 50% of the population |
|
|
Term
|
Definition
| THe toxic dose that is produced in 50% of the population |
|
|
Term
|
Definition
| The lethal dose that will cause death in 50% in the population |
|
|
Term
| Steady State concentration: |
|
Definition
| when multiple doses of a drug, after being administered, leves oss becoming bioavailably equal to the rate of metabolism or excretion |
|
|
Term
|
Definition
| Given so many times a day where drug clearance and drug absorbtion are equal |
|
|
Term
|
Definition
| Dose administered at a regular dosing interval on a repetitive basis. |
|
|
Term
|
Definition
| one or more doses are higher than the maintenance dose and administered at the beginning of therapy for achievin the therapeutic concentration quicker. |
|
|
Term
|
Definition
| Oversees and regulates the manufacturing, repackaging and labeling of perscription drugs. |
|
|
Term
|
Definition
| Oversees licensure and certification of all locations where controlled substances are ordered, recieved, stored, administered, or dispensed. |
|
|
Term
|
Definition
| Responsible for contamination, storage, disposal, and public exposure to medication risks |
|
|
Term
|
Definition
| Responsible for regulating medications transported ocer state lines that have not ye tbeen prescribed/dispensed to the patient. |
|
|
Term
| Federal Food, Drug and Cosmetic act: |
|
Definition
| Established to regulate saftey, quality, purity, strength, and labeling of drugs. 1938 |
|
|
Term
| Federal Comprehensive Drug Abuse Prevention and Control Act: |
|
Definition
| DEA assumes responsibility of regulating the manufacture, distribution, and dispensing of drugs that have potential of abuse. |
|
|
