Term
|
Definition
|
|
Term
| what does the dopamine difeciency lead to? |
|
Definition
|
|
Term
| what are some of the characteristics of parkinsons? |
|
Definition
Tremors of head and neck
Rigidity (increased muscle tone)
Bradykinesia (slow movement)
Postural changes
Head and chest thrown forward
Shuffling walk
Lack of facial expression
Pill-rolling motion of hands |
|
|
Term
| What are the drugs used for parkinsons? |
|
Definition
| anticholernergics, dopaminergics, dopamine agonists, MAO-B inhibitors, and COMT inhibitors |
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|
Term
| what are side affects of anticholinergics? |
|
Definition
|
|
Term
| what do the anticholinergics do? |
|
Definition
| they block cholinergic receoptors |
|
|
Term
| what do dopaminergics do? |
|
Definition
|
|
Term
| what are some of the anticholinergics that are used? |
|
Definition
| benztropine (cogentin) and trihexyphenidyl HCL (artane) |
|
|
Term
| what is a dopaminergics drugs? |
|
Definition
| carbidopa-levodopa (sinemet) |
|
|
Term
| what do dopaminergics do? |
|
Definition
|
|
Term
| what are the side effects of dopaminergic drugs? |
|
Definition
Fatigue, insomnia, dry mouth, blurred vision
Orthostatic hypotension, palpitations, dysrhythmias
Urinary retention, nausea, vomiting
Dyskinesia, psychosis, severe depression |
|
|
Term
| what drugs decrease levodopa effects? |
|
Definition
Fatigue, insomnia, dry mouth, blurred vision
Orthostatic hypotension, palpitations, dysrhythmias
Urinary retention, nausea, vomiting
Dyskinesia, psychosis, severe depression |
|
|
Term
what is a dopamine agonists? |
|
Definition
|
|
Term
| what does amantadine (symmetrel) do? |
|
Definition
| it stimulates dopamine receptors |
|
|
Term
| What is the pathospysiology of alzheimer's disease? |
|
Definition
Progressive, degenerative disease
Neuritic plaques form
Neurofibrillary tangles are in neurons
Cholinergic neurotransmitter abnormality |
|
|
Term
| what are some of the characteristics of Alzheirmers? |
|
Definition
Loss of memory, logical thinking, judgment
Time disorientation
Personality changes
Hyperactivity
Tendency to wander
Inability to express oneself |
|
|
Term
| what are some of the acetylcholinesterase inhibitors? |
|
Definition
| donepril (aricept) and Rivastigmine (exelon) |
|
|
Term
| what do acetylcholinesterase inhibitors do? |
|
Definition
| they allow more acetylcholine in neuron receptors |
|
|
Term
| what are some of the side effects of acetylcholinesterase inhibitors? |
|
Definition
Headache, dizziness
Depression
GI distress
Dehydration, dry mouth
Blurred vision
Insomnia
Hypertension, hypotension, dysrhythmias
Hepatotoxicity |
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