Term
| Higher incidence of squamous cell carcinoma of the esophagus? |
|
Definition
|
|
Term
| Higher incidence of adenocarcinoma of the esophagus? |
|
Definition
|
|
Term
| What are the major causes in the US of esophageal cancer? |
|
Definition
1) smoking
2) alchol consumption |
|
|
Term
| What is high risk factor for adenocarcinoma besides alcohol and smoking? |
|
Definition
| GERD - barrett esophagus - 40-125x |
|
|
Term
| What oncogene is the most critical in SCC esophageal cancer and is associated w/ a poor prognosis? |
|
Definition
|
|
Term
| What clinical manifestation is present in 90% of people with esophageal cancer? |
|
Definition
|
|
Term
| What has a 100% accuracy for diagnosis of esophageal cancer? |
|
Definition
|
|
Term
| What are 3 risk factors gastric cancer? |
|
Definition
1) dietary factors - nitrates
2) infections - H. pylori
3) familial syndromes |
|
|
Term
| What type of tumors are 95% of gastric tumors? |
|
Definition
|
|
Term
| What are the most common symptoms associated with gastric cancer? |
|
Definition
| 1) abdominal/epigastric pain w/weight loss |
|
|
Term
| Pareneoplastic syndromes associated with gastric cancer? |
|
Definition
1) acanthosis nigricans
2) dermatomyositis
3) circinate erythemas
4) pemphigoid
5) seborrheic keratosis |
|
|
Term
| What diagnostic test has an accuracy of 95% for gastric cancer? |
|
Definition
|
|
Term
| What part of pancreas is responsible for 95% of cancers? |
|
Definition
|
|
Term
| There is a higher rate of pancreatic cancer in whom? |
|
Definition
|
|
Term
| What is the most accurate test for imaging and staging of pancreatic carcinoma? |
|
Definition
|
|
Term
| What is the only curable treatment for pancreatic cancer? |
|
Definition
| surgery-whipple procedure (pancreaticoduodenectomy) |
|
|
Term
| What is the most common primary malignant tumor of the liver? |
|
Definition
|
|
Term
| What is the most common presentation with hepatocellular carcinoma? |
|
Definition
1) R upper quadrant pain
2) epigastric pain |
|
|
Term
| what are the pareneoplastic syndromes associated with hepatocellular carcinoma? |
|
Definition
1) hypoglycemia
2) hypercalcemia
3) erthrocytosis
4) PORPHYRIA CUTANEA TARDA |
|
|
Term
| What is the only curative treatment for hepatcellular carcinoma? |
|
Definition
| surgery - high recurrence rate of 75% |
|
|
Term
| What type of cancers are most Anal cancers? |
|
Definition
|
|
Term
| What are associated with premalignant lesions with anal cancer? |
|
Definition
1) HPV infection
2) conylomata acuminata |
|
|
Term
| What is imatginib mesylate and what is it used for? |
|
Definition
1) signal transduction inhibitor
2) successful treatment of unresectable tumors |
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