Term
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Definition
| Sheath that surrounds hyaline cartilage (except articular surfaces) and includes CARTILAGE PROGENITOR CELLS |
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Term
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Definition
| Pairs of chondrocytes, which represent 2 daughter cells of a previous mitotic division |
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Term
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Definition
| Cells that synthesize fibers and ECM of cartilage |
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Term
| Describe the orientation of collagen fibers in hyaline joint cartilage |
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Definition
| Collagen near the surface is parallel to surface. Near the bone it is oriented vertically. Made mostly of type II collagen. |
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Term
| Cartilage is formed by what type of embryonic cell? |
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Definition
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Term
| Describe appositional growth |
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Definition
| This is growth at the edge of the cartilage |
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Term
| Describe interstitial growth |
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Definition
| Growth from the middle of the cartilage. Isogenic chondrocytes spread apart by secreting ECM. |
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Term
| An increase in _________ promotes bone formation over cartilage formation. |
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Definition
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Term
| Is interstitial cartilage growth possible in adults? |
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Definition
| No. Chondrocytes do not divide in adults, so no interstitial growth is possible. (Appositional growth in adults is limited). |
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Term
| Differentiate between Hyaline cartilage and Elastic cartilage. |
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Definition
1)Hyaline is found at joints, trachea, costal cart. and developing bones. Elastic cartilage is found in the ears and epiglottis.
Elastic cartilage has the same composition as Hyaline but also contains sheets and fibers of Elastin. |
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Term
| Does fibrocartilage habe a perichondrium? |
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Definition
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Term
| What fibers compose Fibrocartilage? |
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Definition
| Type I and type II colagen. |
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Term
| Does Fibrocartilage calcify easily? |
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Definition
| No- it doesn't tend to calcify at all. |
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Term
| List 3 functions of Bone: |
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Definition
| a) stucture b)calcium & mineral reservoir c) contains blood and CT forming tissue (marrow) |
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Term
| How do the proteoglycan and water content of bone relate to that of cartilage? |
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Definition
| Bone has much less water (5% compared to 65%) and a lower proteoglycan content than cartilage. |
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Term
| Bone contains primarily type ___________ fibers. |
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Definition
| type I collagen (about 90%) |
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Term
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Definition
| Hypoxyapetite crystals are the Ca2+ / PO4- minerals that make up bone. Constitutes 65% of bone by weight & binds to collagen and ground substance. |
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Term
| A certain defect in type I collagen can lead to ____________, a disease which causes bones to fracture easily |
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Definition
| What is: Osteogenesis imperfecta |
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Term
| What disease is characterized by flexible bones, due to a loss of Calcium? |
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Definition
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Term
| Bone is surrounded by _________, which is analogous to perichondrium of cartilage. |
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Definition
periostium.
(note that it DOES exist on articular surfaces, unlike perichondrium in cartilage) |
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Term
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Definition
| Endosteum is the interior surface of bones. It is lined with progenitor cells. |
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Term
| Periosteum has 2 layers, the inner and outer. Differentiate between them. |
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Definition
Outer- fibrous, dense connective tissue.
Inner- contains osteoprogenitor cells. |
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Term
| What phagocytic cells 'eat' bone? |
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Definition
| Osteoclasts. They eat bone in order to remodel it. Derived from hematopoetic cells. |
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Term
| The ground substance of cartilage contains a large amount of __________ which stains ________. |
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Definition
| sulfated proteoglycans, basophilic |
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Term
| The histological preperation used to view STRUCTURES of bone is: |
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Definition
| Ground Bone - a process which destroys cells |
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Term
| The histological process used to view bone cells is: |
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Definition
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