Term
| Rx only topical treatment for osteoarthritis (can be $40/tube!) |
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Definition
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Term
| Salicylate topical treatment |
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Definition
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Term
| Menthol/salicylate combo topical treatments |
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Definition
| BENGAY, Icy-Hot, Salonpas |
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Term
| Inhibits substance P, which is involved in signaling for pain, modifying over time but not blocking it |
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Definition
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Term
| May be helpful in reducing pain for a very specific painful area (i.e. back); can be expensive (30 patches are over $200) |
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Definition
| Lidoderm Patch (Rx), Lidocaine topical |
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Term
| Centrally-acting prostaglandin inhibitor; considered first-line oral in osteoarthritis |
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Definition
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Term
| Peripheral prostaglandin inhibition through COX-1 and COX-2; provide pain and anti-inflammatory effect |
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Definition
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Term
| "housekeeping functions" prostaglandins involved in everyday functions |
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Definition
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Term
| involved in inflammation/pain |
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Definition
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Term
| Helpful for preventing NSAID-induced ulcer and potentially causes substantial GI effects |
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Definition
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Term
| Higher failure rate, may not be helpful in GI ulcer prevention |
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Definition
| Antacids, H2 blockers, sucralfate |
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Term
| Considered more selective for Cox-2 so may be used with PPI over older NSAIDs for OA |
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Definition
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Term
| salsalate, choline-magnesium salicylate |
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Definition
| non-acetylated salicylates |
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Term
| weaker than some NSAIDs but easier on stomach and devoid of anti-platelet effects; may not be as effective on pain relief |
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Definition
| salsalate, choline-magnesium salicylate |
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Term
| may decrease blood flow to kidney as well as increase fluid retention |
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Definition
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Term
| NSAIDs may interfere with the ability of this to work |
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Definition
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Term
| Used to try to help rebuild cartilage, take some time to take effect |
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Definition
| Glucosamine, Chondroitin, MSM |
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Term
| possible increase in blood glucose but debated, better evidence for efficacy |
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Definition
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Term
| similar to heparin and may increase bleeding risk |
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Definition
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Term
| overall well tolerated, works pretty well, watch for sulfa allergy |
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Definition
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Term
| May be required for severe cases,watch CNS effects, respiratory depression watch in pts w/ COPD, prevent constipation! |
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Definition
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Term
| Used to lubricate joint, used in the knee, injections, considered to be medical device rather than a drug |
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Definition
| Sodium Hyaluronate, Hyaluronic acid |
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Term
| may be useful for acute pain, helpful for pts with local inflammation and joint effusion, have limits on doses |
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Definition
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Term
| For some patient may be more effective treatment, encourage patients to get further evaluation if this has not been done |
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Definition
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