Term
| How do most drugs get to the target receptor? |
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Definition
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Term
| What are two lipid soluble functional groups on drugs? |
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Definition
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Term
| What are two water soluble groups on drugs? |
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Definition
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Term
| Will a drug that burns or stings increase its concentration or decrease the drug concentration? |
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Definition
| Burning or stinging increases tear flow, thus diluting the drug |
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Term
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Definition
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Term
| What pKa of drugs will be abosorbed in the stomach? |
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Definition
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Term
| Where are most drugs absorbed when taken orally? |
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Definition
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Term
| What are two disadvantages of IV administration? |
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Definition
aseptic technique risk of overdose less margin for error because drug is going into systemic circulation
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Term
| What is the safest and most convenient form of administration? |
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Definition
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Term
| What effect does epinephrine have on the local and systemic distribution of a drug? |
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Definition
| Epinephrine constricts blood vessels and keeps the drug more concentrated at the local site |
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Term
| What organ metabolizes most hydrophilic drugs? |
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Definition
| kidneys are favored with renal excretion |
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Term
| What organ metabolizes drugs excreted in bile and the feces? |
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Definition
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Term
| What property of a drug limits the frequency of dosing? |
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Definition
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Term
| What is the percentage of compliance for a 1 qid administration vs. a tid administration? |
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Definition
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Term
| What effect does inflammation have on drug distribution? |
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Definition
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