Term
Ibuprofen
A: Reversibly inhibits COX
B: Analgesic and antipyritic effects
C: Highly protein bound
D: Chronic use inhibits renal PG production |
|
Definition
|
|
Term
| What TNF drug can be given for JRA if methotrexate and hydroxychloroquine don;t work? |
|
Definition
|
|
Term
| Aspirin triad includes aspirin intolerance and what other 2 symptoms? |
|
Definition
|
|
Term
A child overdosed on aspirin what are the treatments?
|
|
Definition
Alkilization of the urine
Activated charcoal |
|
|
Term
| Chronic use of NSAIDS may result in. |
|
Definition
| Acute renal insufficiency |
|
|
Term
| To prevent bleeding problems during surgery, aspirin should be discontinued __ before surgery |
|
Definition
|
|
Term
Which of the following regarding inflixinab is true?
- It is a chimeric monoclonal antibody
- It neutralizes TNF α
- It is used for RA
- Human antichimeric AB can limit it's use
|
|
Definition
|
|
Term
NSAIDS are counter indicated for patients that have
- Allergy to sulfonamides
- Allergy to NSAIDS
- The aspirin triad
- Methemoglobinemia
|
|
Definition
|
|
Term
Treatment of osteoarthritis include
- Ibuprofen
- Ketorolac
- Celebrex
|
|
Definition
|
|
Term
Which of the following statements regarding aspirin are correct?
- As an antipyritic it is more effective than tylenol
- It is less likely than tylenol to cause GI irritation
- The late stage of overdose includes respiratory and metabolic acidosis
- NAC is the antidote
|
|
Definition
|
|
Term
The glucocorticoid hormones produce which of the following effects?
- Decrease fat deposition
- Inhibit release and synthesis of thromboxone and leukotrienes
- Increase protein synthesis in most tissue
- Lower plasma glucose levels
- An increase in the number of WBC
|
|
Definition
|
|
Term
Accepted use for celebrex include
- Osteoarthritis
- RA
- Famelial adenomatious polyps
- MS
|
|
Definition
|
|
Term
| A patient is treated with a horse derivative Ab, and is experiencing hypersensitivity, what should be used? |
|
Definition
| Lymphocyte Immunoglobulin (Atgam) |
|
|
Term
Renal impairment resulting from chronic NSAID use include
- AKI
- Intestinal nephritis
- papillary necrosis
- inhibition of renal PG production
|
|
Definition
|
|
Term
| Which hypersensitivity involves the Penias? |
|
Definition
|
|
Term
| In a recent study, short term use of recombinant __ reduced the risk of serious infection in CGD patients |
|
Definition
| Interferon gamma (actimmune) |
|
|
Term
Which of the following are steroids not used for?
- RA
- eczima
- conjunctivitis
- glomerularnephritis
- lupus
|
|
Definition
|
|
Term
Signs seen in children OD on ASA
- Hyperthermia
- respiratory & metabolic acidosis at late stage
- Tinnitus
- respiratory alkilosis during early stage
|
|
Definition
|
|
Term
long term administration of Dexamethasone would include all except
- Osteoporosis
- Hypoglycemia
- Peptic ulcer
- Cataracts
- Adrenal cortical suppression
|
|
Definition
|
|
Term
| how should a patient with a goiter and normal T3 and T4 be treated |
|
Definition
| subtotal thyroidectamy and T4 |
|
|
Term
| administration of lugol's solution will result in |
|
Definition
| decreased T4 and T3 in the blood |
|
|
Term
| Alternating therapy should not be done to treat a patient with |
|
Definition
|
|
Term
| The principle MOA of fosamax is to |
|
Definition
| inhibit osteoclast mediated bone resorption |
|
|
Term
Which antiinflamatory steroid should not be given IV?
|
|
Definition
|
|
Term
| Which drug can causes TB? |
|
Definition
|
|
Term
| glucocorticoid produces what effect |
|
Definition
| inhibit synthesis and release of thromboxone and leukotrienes |
|
|
Term
| a high 17-OH and cortisol in the urine means |
|
Definition
|
|
Term
| synthetic antiinflammatory steroids can induce synthesis of lipocortisin which decreases synthesis of proinflammatory |
|
Definition
|
|
Term
| Calcitriol, the active form of vit D can treat osteoporosis because it |
|
Definition
| raises serum Ca, and lowers PTH |
|
|