Term
| Aspirin (Acetylsalicylic acid/ASA) |
|
Definition
| suppresses vasoconstriction |
|
|
Term
| Aspirin (Acetylsalicylic acid/ASA) |
|
Definition
| effect persists for 7-10 days which is life span of platelet |
|
|
Term
| Aspirin (Acetylsalicylic acid/ASA) |
|
Definition
| dose of 81 mg a day is effect ive |
|
|
Term
| Aspirin (Acetylsalicylic acid/ASA) |
|
Definition
| suppress platelet aggregation by causing irreversible inhibition of cyclooxygenase (COX) |
|
|
Term
| Aspirin (Acetylsalicylic acid/ASA) |
|
Definition
| teach pt to check stool for blood teach pt to check for bleeding a/o bruising in other areas |
|
|
Term
| Aspirin (Acetylsalicylic acid/ASA) |
|
Definition
|
|
Term
Aspirin (Acetylsalicylic acid/ASA) versus
Ticlid (Ticlopidine) |
|
Definition
| aspirin persist to duration of platelet and Ticlid (Ticlopidine)outlasts duration of platelet |
|
|
Term
| Aspirin (Acetylsalicylic acid/ASA) |
|
Definition
| may increase risk of hemorrhagic stroke so teach pt/family sxs of this type of stroke |
|
|
Term
| Ticlid (Ticlopidine) and Plavix (clopidogrel) |
|
Definition
| causes irreversible blockade of ADP receptors on the platelet surface thereby suppressing ADP stimulated aggregation |
|
|
Term
|
Definition
| Approved for prevention of ischemic strokes |
|
|
Term
|
Definition
| pts should have CBC every 2 weeks for first 3 months of therapy; after 3 months the risk is low |
|
|
Term
|
Definition
| effects are irreversible and last longer than life span of platelets |
|
|
Term
|
Definition
| fatal hematological effects such as neutropenia, agranulocytosis, thrombo-cytopenia purpura (TTP) |
|
|
Term
|
Definition
| Aspirin, Ticlid, Plavix (clopidogrel), Persantine (dipyridamole) |
|
|
Term
|
Definition
|
|
Term
|
Definition
| similar to Ticlid but does not cause neutropenia or agranulocytosis |
|
|
Term
| Persantine (Dipyridamole) |
|
Definition
| Suppresses platelet aggregation; combined with ASA as Aggrenox |
|
|
Term
| Persantine (dipyridamole) and Aspirin combined |
|
Definition
|
|
Term
| Persantine (dipyridamole) |
|
Definition
| used to prevent recurrent stroke in pt with previous stroke or TIA |
|
|
Term
| Persantine (Dipyridamole) |
|
Definition
| teach safety measures r/t dizziness |
|
|
Term
| Persantine (Dipyridamole) |
|
Definition
|
|
Term
|
Definition
| Rapid acting anticoagulant administered only by injection-SQ, IVP or by IVdrip |
|
|
Term
|
Definition
| suppresses coagulation by helping antithrombin inactivate thromgin and factor Xa which ultimately suppresses formation of fibrin clot |
|
|
Term
|
Definition
| does NOT dissolve clots once formed |
|
|
Term
|
Definition
| antidote is Protamine Sulfate |
|
|
Term
|
Definition
| can only be given in hospital |
|
|
Term
|
Definition
| anticoagulant effects occur rapidly; within minutes given by IV |
|
|
Term
|
Definition
|
|
Term
|
Definition
| half-life is short, so when d/c’d, effect is gone within several hours |
|
|
Term
|
Definition
| pts with hepatic or renal problems have longer half life and effects are prolonged |
|
|
Term
|
Definition
| monitor closely for hemorrhage-monitor VS |
|
|
Term
|
Definition
| Heparin induced thrombocytopenia-monitor platelets when pt is receiving |
|
|
Term
|
Definition
| also monitor for thrombotic events |
|
|
Term
|
Definition
| if platelet counts drop <100,000-should be d/c’d |
|
|
Term
|
Definition
| should be avoided immediately after eye surgery, brain or spinal cord surgery |
|
|
Term
|
Definition
| requires careful monitoring of aPTT levels; normal values=40 secs; therapeutic level for anticoagulation is 1.5 to 2 times control or 60-80 seconds; done every 6 hrs |
|
|
Term
|
Definition
| when given SQ do NOT aspirate, put gentle pressure at injection sites 1-2 minutes following injection |
|
|
Term
|
Definition
| always prescribed in UNITS |
|
|
Term
| Lovenox - (low molecular weight Heparin)(Enoxaparin) |
|
Definition
| Shorter version of Heparin |
|
|
Term
| Lovenox - (low molecular weight Heparin)(Enoxaparin) |
|
Definition
| is as effective as Heparin and can be given on fixed dose schedule that does not requires aPTT monitoring |
|
|
Term
| Lovenox - (low molecular weight Heparin)(Enoxaparin) |
|
Definition
|
|
Term
| Lovenox - (low molecular weight Heparin)(Enoxaparin) |
|
Definition
dosing in once or twice daily
-no lab monitoring required |
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
| pt MUST eat a diet consistent in dark, leafy green vegetables (Vit K) so that INR is not affected |
|
|
Term
|
Definition
| therapy with ASA, Tylenol, Heparin and sulfonamide antibiotics will increase risk of bleeding with Coumadin |
|
|
