Term
| Sulfonamides - Sulfamethoxazole |
|
Definition
| Inhibit synthesis of folic acid which is required by cells to make DNA/RNA; indications for use include UTI |
|
|
Term
| Sulfonamides - Sulfamethoxazole |
|
Definition
| FF to maintain adequate hydration to prevent crystallization in kidneys |
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Term
| Sulfonamides - Sulfamethoxazole |
|
Definition
| increase effects of Warfarin, Phenytoin and Sulfonylureas |
|
|
Term
| Sulfonamides - Sulfamethoxazole |
|
Definition
| pts with demonstrated hypersensitivity to sulfa drugs show same sensitivity to thiazide and loop diuretics |
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|
Term
| Sulfonamides - Trimethoprim used in combination with Sulfamethoxazole –TMP/SMZ(Bactrim, Septra, Cotrim) |
|
Definition
| TMP/SMZ drug of choice for prevention of pneumonocystis carini pneumonia with HIV+ pts |
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|
Term
| Sulfonamides - Sulfamethoxazole |
|
Definition
| avoid prolonged exposure to sun while taking and wear protective clothing, apply sunscreen |
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|
Term
| Sulfonamides - Sulfamethoxazole |
|
Definition
-get culture before first dose, check sensitivity report
-monitor WBC counts |
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Term
| Sulfonamides - "Side Effects" |
|
Definition
| hypersensitivity reactions-rash, fever and photosensivity; may cause Steven Johnson Syndrome-severe lesions of skin and mucus membranes, fever, malaise, toxemia |
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|
Term
| Sulfonamides - "Side Effects" |
|
Definition
blood dyscrasias (disorders); renal damage from crystallization; n/v; anorexia
-rash |
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|
Term
| Fluoroquinolones - Medications |
|
Definition
-ciprofloxacin (Cipro)
-levofloxacin (Levaquin)
-ofloxacin (Floxin) |
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|
Term
| Fluoroquinolones - Mechanisms of action |
|
Definition
| Broad spectrum antibiotics used to treat UTI, URI, GI tract, bones, joints |
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|
Term
| Fluoroquinolones - Mechanisms of action |
|
Definition
| inhibit bacterial DNA synthesis; bacteriocidal drug with very rapid action |
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Term
| Fluoroquinolones - Nursing Implications |
|
Definition
| should not be taken with antacids, milk, iron preparations-separate by 6 hrs |
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Term
| Fluoroquinolones - Nursing Implications |
|
Definition
| increases Theophylline levels and Warfarin levels; monitor pts closely for need for dosage adjustment |
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|
Term
| Fluoroquinolones - Nursing Implications |
|
Definition
| pts taking Digoxin have increased risk of developing toxicity |
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Term
| Fluoroquinolones - Nursing Implications |
|
Definition
| monitor WBC counts; maintain u/o 1200-1500 ml/day; check sensitivity report |
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|
Term
| Fluoroquinolones - Nursing Implications |
|
Definition
infuse IV over one hour
-as effective orally as IV |
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|
Term
| Fluoroquinolones - Side Effects |
|
Definition
| tendon rupture-Achilles tendon |
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|
Term
| Fluoroquinolones - Side Effects |
|
Definition
| n/v, diarrhea, abdominal pain,CNS effects-dizziness, HA, restlessness, confusion; visual disturbances in elderly |
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|
Term
| Which medication group has the side effect of possible Achilles tendon rupture? |
|
Definition
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