Term
|
Definition
| Block prostaglandin synthesis, similar to ASA |
|
|
Term
|
Definition
| Acetaminophen may cause hepatic damage especially with long term used and EtOH |
|
|
Term
No GI effects
No heme effects
No assoc. with Reye Syndrome
No CV affects
No resp effects
No acid-base effects |
|
Definition
| How Acetaminophen is different from ASA |
|
|
Term
|
Definition
| Blocks COX-1 and COX-2; inhibits COX-1 better; can induce asthma |
|
|
Term
|
Definition
| Prevention of thrombus post MI, CVA, men >45 and Women>55 |
|
|
Term
|
Definition
| Metab via conjugation at low to moderate doses; excreted by kidneys at high doses |
|
|
Term
|
Definition
| Major side effect is gastric bleeding |
|
|
Term
|
Definition
| Can displace warfarin, methotrexate, sulfonamides |
|
|
Term
|
Definition
| Low doses inc CO2, inc acidity; toxic doses cause metabolic acidosis and hypokalemia |
|
|
Term
|
Definition
| In overdose of this, increased alkalinity of urine with sodium bicarb |
|
|
Term
|
Definition
| A selective COX-2 inhibitor |
|
|
Term
|
Definition
| Used in Osteoarthritis, RA, FAP |
|
|
Term
|
Definition
|
|
Term
|
Definition
| May inhib 2D6 in some people, i.e. may slow metab of tricyclics, SSRIs, antiarrhythmics |
|
|
Term
|
Definition
| An NSAID that does not displace warfarin |
|
|
Term
|
Definition
|
|
Term
|
Definition
| Chronic use may inc risk of MI |
|
|
Term
|
Definition
| Chronic use assoc w/ more ulcer risk than other NSAIDS |
|
|
