Term
| sniffed/injected form of cocaine |
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Definition
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Term
|
Definition
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Term
|
Definition
euphoria
increased sympathetics
high sexual overtones |
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Term
| cocaine plus OH causes this metabolite |
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Definition
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Term
| metabolite of cocaine that lasts 3-4 days |
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Definition
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Term
|
Definition
| inhibits Na channels, blocking initiation and conduction of action potentials |
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Term
| how does cocaine induce sympathetic system |
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Definition
| blockage of the norep transporter |
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Term
| Nictoine overdose effect on CV system |
|
Definition
| intracranial hemorrhage and ischemic stroke |
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Term
| given to pts on cocaine for convulsions |
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Definition
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Term
|
Definition
| injected IV or sniffed into the nasal mucosa |
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Term
| can be formed by OTC pseudoephedrine |
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Definition
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Term
| mech of action amphetamine |
|
Definition
release of norep, dopamine, and serotonin.
inhibition of reuptake |
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Term
| which has greater tolerance, cocaine or amphetamines |
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Definition
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Term
|
Definition
bruxism
thin, hyperactive paranoid user |
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Term
| what is tar in cigarrettes responsible for |
|
Definition
lung cancer
emphysema
bronchial disorders |
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|
Term
| carbon monoxide in cigarretes |
|
Definition
| increased chance of cardiovascular disease |
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Term
| these are the most likely causes of cancer assoc w/smoking |
|
Definition
Aromatic amines
nitrosamines
polyaromatic hydrocarbons |
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Term
| chief metabolic product of smoking |
|
Definition
cotinine
carboxyhemoglobin also good indication of recent smoking |
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|
Term
|
Definition
slower rise in nicotine levels
reduce cravings.
has to be motivated |
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|
Term
|
Definition
inflexible doses
dermatology problems
effective during early treatment |
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Term
| varenicline mech of action |
|
Definition
partial ag at alpha4beta2 nicotoine receptors
prevents release of dopamine
**superior to buproprion** |
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|
Term
| adverse effects of varenicline |
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Definition
90% suicides
exacerbation of psychiatric illness |
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