Term
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Definition
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Term
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Definition
| mutation (Tyr402His) is a risk for macular degeneration |
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Term
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Definition
| secreted in response to hypoxia |
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Term
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Definition
| hydroxylate HIF-1a so it can be ubiquitinylated, inhibited by hypoxia |
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Term
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Definition
| complexes with HIF-B and p300/CBP, induces VEGF and erythropoietin |
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Term
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Definition
| complexes with HIF-1a, induces VEGF and erythropoietin |
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Term
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Definition
| secreted by RPE, stimulate macrophages to produce TNF and TGF-B (scarring in macular degeneration) |
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Term
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Definition
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Term
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Definition
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Term
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Definition
| closed by light, causes hyperpolarization as K+ escapes photoreceptor cell |
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Term
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Definition
| scotopsin and 11-cis-retinal |
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Term
| BathoLumiMeta I-II ScoRho |
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Definition
| transition states of rhodopsin after excitement by light |
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Term
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Definition
| activated by trans pigment, stimulates cGMP-phosphodiesterase |
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Term
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Definition
| mutated in Charcot-Marie Tooth Disease |
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Term
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Definition
| biomarker for small-cell lung carcinoma |
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Term
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Definition
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Term
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Definition
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Term
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Definition
| slow-wave sleep substance, contained in median raphe nuclei |
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Term
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Definition
| fired during REM by gigantocellular nucleus |
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Term
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Definition
| decrease firing in REM in locus cerleus |
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Term
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Definition
| fire when awake, decrease during sleep in lateral hypothalamus |
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Term
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Definition
| high activity when awake, decrease during sleep in hypothalamus |
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Term
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Definition
| increases during sleep, inhibits wakeful areas in ventrolateral preoptic hypothalamus |
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Term
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Definition
| isolated from CSF & blood, produces non-REM sleep when injected into 3rd ventricle, increased synthesis during wakefulness until it induces sleep |
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Term
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Definition
| secreted by pineal body, increased in darkness, decreased in light, some initiation of sleep, used to treat jet-lag and insomnia |
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Term
| ATP, chormogranins, neuroactive peptides, dopamine B-hydroxylase |
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Definition
| found in synaptic vessicles and chromaffin granules |
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Term
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Definition
| smooth muscle contraction, activate Gaq, PLC converts PIP2 to DAG&IP3, increases Ca2+ |
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Term
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Definition
| presynaptic membrane, provide NE feedback, activate Gai, decrease cAMP/PKA/Ca2+/NE, increase vagal tone, decrease GI tone and motility |
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Term
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Definition
| smooth muscle relaxation, activate Gas, increase adenylate cyclase/cAMP/cGMP, decrease P-myosin, increase glycogen breakdown |
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Term
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Definition
| in gallbladder and brain tissue, increase lipolysis and FFAs |
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Term
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Definition
| on myocardium and impulse-conducting tissues, increase HR/impulse/contractility/myocardial relaxation |
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Term
| Renin, Angiotensin II, vasopressin |
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Definition
| Mean arterial pressure (MAP) increased by B1 effects |
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Term
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Definition
| most in liver/mitochondria of CA nerve terminals, converts CAs to MHPG |
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Term
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Definition
| in effector cells, converts CAs to methoxylated derivatives |
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