Term
| Lifetime prevalence of major depression |
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Definition
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Term
| Major depression likelihood based on sex |
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Definition
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Term
| Does family history play a role in major depression? |
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Definition
| It can but it is not that common |
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Term
| Mean age for major depression |
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Definition
| 40 but can occur at any age |
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Term
| Societal spread of major depression |
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Definition
| occurs in all socioeconomic classes and races |
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Term
| Untreated major depression can last for |
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Definition
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Term
| treated major depression can be resolved |
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Definition
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Term
| Risk of recurrence for major depression |
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Definition
Rule of thirds
1/3 will not have it again, 1/3 will have sporadic episodes, 1/3 will have repetitive recurrent episodes |
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Term
| Major depression symptoms |
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Definition
| change in sleep pattern, change in appetite, decreased energy, suicidal, decreased concentration and memory, depressed mood, helplessness, irritability, excessive guilt, psychosis |
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Term
| Major depression diagnosis is |
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Definition
| 5 or more symptoms for 2 wks duration |
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Term
| Differential diagnosis for major depression |
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Definition
| major depression, bipolar depression, dysthymia, grief, adjustment disorder, hypothyroidism, substance induced, stimulant w/d, chf, hypoxia, parkinsons, HIV, adrenal disorders |
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Term
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Definition
| chronic low grade depression |
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Term
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Definition
| Tryptophan->tryptophan hydroxylase->5-hydroxytryptophan->aa decarboxylase->serotonin |
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Term
| Missing tryptophan from diet |
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Definition
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Term
| What enzymes breakdown serotonin |
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Definition
| Monoamine Oxidase and Aldehyde Dehydrogenase |
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Term
| If you block MAO what happens to serotonin in cells |
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Definition
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Term
|
Definition
| selective serotonin reuptake inhibitor blocks serotonin reuptake into cell so get increased serotonin levels in synapse |
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Term
| Lifetime Suicide risk for major depression |
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Definition
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Term
| During single episode of MDD,... consider suicide |
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Definition
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Term
| Antidepressant treatments |
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Definition
1. SSRI-60-70% efficacy
2. SNRI-serotonin NE reuptake inhibitor
3. Tricyclics-ambotriptiline
4. MAOI-monoamine oxidase inhibitors |
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Term
| Schizophrenia lifetime prevalence |
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Definition
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|
Term
| Sex difference between schizophrenia |
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Definition
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|
Term
|
Definition
Males-late teens
Females-early 20's |
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Term
| Schiz racial prevalance difference |
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Definition
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|
Term
| Schiz socioeconomic class correlation |
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Definition
| their appears to be some evidence |
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Term
| Schizophrenia positive symptoms |
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Definition
1.delusions
2.paranoia
3.hallucinations-auditory or visual
4.Disorganized thought process |
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Term
|
Definition
1.blunted affect
2. alogia
3. Social isolation
4. lack of motivation
5. Anhedonia-inability to enjoy
6. poor hygeine |
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Term
|
Definition
| Paranoid, disorganized, catatonic, undifferentiated |
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Term
|
Definition
| lifelong illness with psychotic exacerbations that tend to come and go and the negative symptoms tend to be chronic and longstanding |
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Term
| Schiz differential diagnosis |
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Definition
psychosis, schizoidal PD- -symptoms,
schizotypal PD- + symptoms, Delirium, schizoaffective disorder |
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Term
|
Definition
| Genetic,catecholamines/serotonin, psychoanalytic-ie needs to talk |
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Term
|
Definition
| dopamine theory, genetic, psychosocial theories |
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Term
| Dopamine theory for schiz two parts |
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Definition
1.mesolimbic
2.mesocortical |
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Term
| Mesolimbic dopamine theory |
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Definition
| too much dopamenergic activity in the mesolimbic areas of the brain explains + symptoms |
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Term
| Mesocortical dopamine theory |
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Definition
| too little dopamenergic activity in the mesocortical regions of the brain explains - symptoms |
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Term
| Schiz lifetime suicide risk |
|
Definition
|
|
Term
|
Definition
1.typical antipsychotics
2.atypical |
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|
Term
|
Definition
| D2 blockers (dopamine receptor 2 blockers) help + symptoms but not negative ones |
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Term
|
Definition
| 5HT2 blockers prevent + and seem to decrease - symptoms because blocks serotonin receptor in mesocortical region which enhances dopamine effect |
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