Term
| Most common intracranial adult tumor? |
|
Definition
|
|
Term
| What is the most common location for metastatic carcinomas of the brain? |
|
Definition
| axial location (grey/white junction) |
|
|
Term
| What does extra-axial brain tumor mean? |
|
Definition
| outside of the brain parenchyma |
|
|
Term
| What phakomotoses increases risk for meningioma's? |
|
Definition
|
|
Term
| common age for meningioma's? |
|
Definition
|
|
Term
| Common sites for meningioma's? |
|
Definition
| parasagittal, sphenoid ridge, spinal cord |
|
|
Term
| Treatment for meningioma? |
|
Definition
|
|
Term
|
Definition
|
|
Term
| Growth characteristics of meningioma? |
|
Definition
| slow growing, benign, compresses brain, doesn't invade, well-circumscribed |
|
|
Term
| Cellular whorls of arachnoid cells are found in what tumor? |
|
Definition
|
|
Term
| Bilateral schwannoma's indicate? |
|
Definition
|
|
Term
| Treatment for schwannoma? |
|
Definition
|
|
Term
| Can schwannoma be removed without damaging nerve? |
|
Definition
|
|
Term
| http://library.med.utah.edu/WebPath/CNSHTML/CNS187.html |
|
Definition
|
|
Term
| Antoni A is described as? |
|
Definition
| cellular with palisading nuclei (schwannoma) |
|
|
Term
| Antoni B is described as? |
|
Definition
| loose, less cellular areas (schwannoma) |
|
|
Term
| What is a verocay body and is found in what tumor? |
|
Definition
| intervening anuclear zone between palisading nuclei |
|
|
Term
| Circumscribed astrocytoma's are found at what site and in what age group? |
|
Definition
| midline tumors found especially in cerebellum and optic nerve and found in children/young adults |
|
|
Term
| Diffuse astrocytoma's are what grades? |
|
Definition
|
|
Term
| Circumscribed astrocytoma known as? |
|
Definition
| juvenile pilocytic astrocytoma |
|
|
Term
| This slow growing tumor has elongated spindle-shaped astrocytes, hyper and hypodense areas with microcysts, and like other slow growing tumors can have Rosenthal fibers? |
|
Definition
| Juvenile pilocytic astrocytoma |
|
|
Term
| What do astrocytoma's usually stain positive for? |
|
Definition
| GFAP (glial fibrillary acidic protein) |
|
|
Term
| Grade II astrocytoma's look similar to normal neuropil but as grade increases what happens? |
|
Definition
| astrocyte proliferation, vascular proliferation, necrosis |
|
|
Term
| Grade IV astrocytoma aka? |
|
Definition
|
|
Term
| glioblastoma's are histologically described as? |
|
Definition
| highly cellular, pleomorphic, hyperplastic vascularity (glomeruloid looking vascular proliferation), mitoses, and necrosis |
|
|
Term
| Going from low grade astrocytoma to high grade there are cumulative gene abnormalities, two of these include? |
|
Definition
| p53 mutations and Loss of heterozygosity of c'some 10 |
|
|
Term
| what's the prognosis for glioblastomas? |
|
Definition
|
|
Term
| What's the prognosis for low grade astrocytoma's |
|
Definition
|
|
Term
| What type of response do diffuse astrocytoma's have to chemotherapy? |
|
Definition
|
|
Term
| Site of oligodendrogliomas? |
|
Definition
|
|
Term
| This tumor is poorly circumscribed, infiltrative, hemorrhagic, and has focal calcification in the cerebral hemispheres with a prognosis of 5 year survival? |
|
Definition
|
|
Term
| fried egg appearance with perinuclear halo appearance and calcifications are seen in this tumor? |
|
Definition
|
|
Term
| Chicken-wire vascular pattern, identified with factor VIII ab seen in this tumor type? |
|
Definition
|
|
Term
| oligodendroglial tumors go through similar changes as what other tumor type to become malignant? |
|
Definition
|
|
Term
| Treatment for oligodendroglial tumor? |
|
Definition
|
|
Term
| Supratentorial ependymoma's found in what age group? |
|
Definition
|
|
Term
| Common presentation for ependymoma? |
|
Definition
| symptoms of CSF obstruction |
|
|
Term
| Common site for ependymoma's? |
|
Definition
| 4th ventricle and spinal cord |
|
|
Term
| These tumors are granular and flake off easily which enables them to seed this area? |
|
Definition
|
|
Term
| Perivascular pseudorosettes are key diagnostic features of this tumor? |
|
Definition
|
|
Term
| medulloblastoma's affect this patient population |
|
Definition
|
|
Term
| In younger patients medulloblastomas are typically found here in young? here in old? |
|
Definition
| cerebellar vermis, lateral hemisphere of cerebellum |
|
|
Term
| Medulloblastoma's can seed this area? |
|
Definition
|
|
Term
| Small, round blue cell tumor in cerebellum? |
|
Definition
|
|
Term
| Rosette formation (blue cell tumor on pink neuropil fibrillary background) in this tumor? |
|
Definition
| medulloblastoma (other rosette's found in PNET) |
|
|
Term
| This can be found next to a variety of slow growing tumors? |
|
Definition
| Rosenthal fibers (pink beaded arrangement of astrocytic glial filaments) |
|
|
Term
| http://img.medscape.com/fullsize/migrated/439/170/nf439170.fig2.jpg |
|
Definition
| juvenile pilocytic astrocytoma (circumscribed astrocytoma) |
|
|
Term
| http://upload.wikimedia.org/wikipedia/commons/f/ff/Glioblastoma_(1).jpg |
|
Definition
|
|
Term
| http://www.ajronline.org/content/vol181/issue1/images/large/07_AC1286_01E_color.jpeg |
|
Definition
|
|
Term
| Tumor with chicken-wire vascular pattern? |
|
Definition
|
|
Term
| Tumor you think of when there are Perivascular Pseudorosettes? |
|
Definition
|
|
Term
| Homer Wright type rosettes? |
|
Definition
| Medulloblastoma with blue cells |
|
|
Term
| http://moon.ouhsc.edu/kfung/IACP-OLP/APAQ-Images/N1-TU-01-17.gif |
|
Definition
| rosettes seen in medulloblastoma |
|
|