Term
| What does the K antigen of bacteria do? |
|
Definition
| inhibits phagocytosis by WBCs |
|
|
Term
| What characteristics of the urine make it antibacterial? |
|
Definition
| low pH, high osmolarity, high urea content |
|
|
Term
| How do Tamm-Horsfall proteins contribute to host defense of the UT? |
|
Definition
| bind bacteria and prevent adherence |
|
|
Term
| What age group has the greatest risk for UTI's? |
|
Definition
|
|
Term
| What are the causitive pathogens of UTI's? |
|
Definition
| E coli, S saprophyticus, S aureus, pseudomonas, enterococci, yeast |
|
|
Term
| For what population group is asymptomatic bacteriuria a concern and why? |
|
Definition
| pregnant women because it is associated with premature labor |
|
|
Term
| complications of acute uncomplicated pyelonephritis |
|
Definition
| perinephric or intrarenal abscess, emphysematous pyelo, obstruction |
|
|
Term
| What population group is most likely to get emphysematous pyelonephritis as a complication of acute uncomplicated pyelo? |
|
Definition
|
|
Term
| How does acute uncomplicated pyelo cause obstruction? |
|
Definition
| renal stones, stricture, papp necrosis |
|
|
Term
| Who gets a complicated UTI? |
|
Definition
| pregnant women, men, children, men/women w/structural or fxnl abnormalities of urinary tract: obstruction, ^ post-void residual, renal transplatation, DM, PKD, ileal-loop, immunosuppresion |
|
|
Term
| What results from a urine dipstick in a patient with a UTI? |
|
Definition
| leukocyte esterase, nitrites |
|
|
Term
| How do you treat acute uncomplicated cystitis? When do you treat for 7-14 days? |
|
Definition
| TMP/SMX, fluoroquinolone, amoxicillin, cephalosporin, nitrofuranton treat for 7-14 days if symptoms have been >7 days, recent UTI, pregnant, DM, or age >65 |
|
|
Term
| What is the duration of treatment for acute uncomplicated pyelo? |
|
Definition
| 14 days, or 2-6 weeks for relapse |
|
|
Term
| How do you treat uncomplicated pyelo in inpatient v outpatient? |
|
Definition
inpatient: fluoroquinolone, 3rd gen cephalosporin, penacillin, B lactam inhib
outpatient: fluorquinolone, amoxicillin, cephalosporin |
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