Term
| The --- induces differentiation of somites, which further differentiate into ----, ---- and ----. |
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Definition
| The notochor induces differentiation of somites which further differentiate into myotome, dermatome and sclerotome |
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Term
What does the lateral plate differentiate into and what are these structures associated with?
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Definition
The lateral plate differentiates into
splanchnopleure -- associated with internal organs
and
somatopleure -- associated with body wall. |
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Term
| What is the intermediate mesoderm reffered to as (what does it generate)? |
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Definition
| Nephrogenic (makes the kidneys and most of the reproductive organs) |
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Term
| When do we get early differentiation of somites? |
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Definition
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Term
| what structures does the neural crest contribute to in the head? |
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Definition
| Neural crest in the body gives rise to peripheral nn system elements, but in the head it also contributes to connective tissue elements - flat bones of skull and cartilage. |
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Term
| what structure do the mm of the body come from and when do they migrate to their final location? |
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Definition
| All mm of the body come from dermomyotome (originally somite), and the migrate to their final location begining of the 5th wk. |
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Term
| where do the vertabrae and intervertebral discs come from? |
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Definition
| They come from the sclerotome part of the somites |
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Term
| where does the body skeleton come from (other than the vertebrae)? |
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Definition
| The Somatopleure, which is part of the lateral plate mesoderm. |
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Term
| This initiates differentiation in tissues under BMP influence. |
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Definition
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Term
| The outer edge of the limb bud expresses this gene. |
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Definition
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Term
| What do WNT and BMP4 do to somites? |
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Definition
| Their dorsal influence differentiates somites into deromomyotome. |
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Term
| What is the influence of shh on sclerotome? |
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Definition
| SHH from notochord has a ventral influence that differentiates the sclerotome. |
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Term
| What do epaxial mm make, what are they innervated by? |
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Definition
| They originate from dermomyotome and make up the deep back mm, which are innervated by the dorsal rami of spinal nn. |
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Term
| What do hypaxial mm make, what is their innervation? |
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Definition
Hypaxial mm originate from dermamyotome, migrate outside of the blastimal skeleton from somatopleure and make appendicular and body wall mm. they are innervated by ventral rami of spinal nn.
WNT, SHH, and BMP are the major influence. |
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Term
| What influences do SHH and Retinoic acid have on developement? |
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Definition
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Term
| What are HOX genes involved in? |
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Definition
| HOX genes regulate bone type and shape. |
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